Cyclopentanecarboxylicacid,2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-,(1R,2R)- cas no:7184-60-3

NameCyclopentanecarboxylicacid,2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-,(1R,2R)-
CAS7184-60-3
Synonyms2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)-cyclopentanecar boxylic acid;Treponemycin;NSC 216128;BRN 0066270;AC1O5MFI;B1936_SIGMA;(1R,2R)-2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl]cyclopentane-1-carboxylic acid;
Molecular FormulaC₂₈H₄₃NO₆
Molecular Weight489.64

AppearanceWhite to Off-White Powder
refractive index1.538
storage temp−20°C

Safety

Poison by subcutaneous, intravenous, and intramuscular routes. When heated to decomposition it emits toxic fumes of NO_x.

1.		scu-rat LD50:1780 µg/kg		JCINAO    Journal of Clinical Investigation. 28 (1949),1047.
2.		ivn-rat LD50:2 mg/kg		85ERAY    Antibiotics: Origin, Nature, and Properties. 2 (1978),1198.
3.		scu-mus LD50:75 mg/kg		JCINAO    Journal of Clinical Investigation. 28 (1949),1047.
4.		ivn-mus LD50:39 mg/kg		JCINAO    Journal of Clinical Investigation. 28 (1949),1047.
5.		ims-ckn LD50:74 mg/kg		85ERAY    Antibiotics: Origin, Nature, and Properties. 2 (1978),1198.