1,3-Benzenedisulfonamide,4-chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]- cas no:7195-27-9

Name1,3-Benzenedisulfonamide,4-chloro-N1-methyl-N1-[(tetrahydro-2-methyl-2-furanyl)methyl]-
CAS7195-27-9
Synonymsm-Benzenedisulfonamide,4-chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)- (7CI,8CI);4-Chloro-N1-methyl-N1-(tetrahydro-2-methylfurfuryl)-m-benzenedisulfonamide; B1500; BAY 1500; Baycaron; FBA 1500; FDA 1902; Mefrusid; Mefruside;N-(4-Chloro-3-sulfamoylbenzenesulfonyl)-N-methyl-2-furfurylamine;N-(4'-Chloro-3'-sulfamoylbenzenesulfonyl)-N-methyl-2-aminomethyl-2-methyltetrahydrofuran
EINECS(EC#)230-562-4
Molecular FormulaC13H19 Cl N2 O5 S2
Molecular Weight382.91

refractive index1.571

Safety

Mildly toxic by intraperitoneal route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl⁻, SO_x, and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	oral	> 5gm/kg (5000mg/kg)	BEHAVIORAL: EXCITEMENT BEHAVIORAL: FOOD INTAKE (ANIMAL)	Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 659, 1967.
dog	LD50	oral	> 5gm/kg (5000mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: FOOD INTAKE (ANIMAL) BEHAVIORAL: ATAXIA	Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 659, 1967.
mouse	LD50	intraperitoneal	5200mg/kg (5200mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 1003, 1973.
mouse	LD50	intravenous	500mg/kg (500mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 659, 1967.
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 1003, 1973.
mouse	LD50	subcutaneous	5200mg/kg (5200mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 386, 1975.
rabbit	LD50	oral	> 3gm/kg (3000mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 659, 1967.
rat	LD50	intraperitoneal	9800mg/kg (9800mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE	Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 1003, 1973.
rat	LD50	intravenous	500mg/kg (500mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 659, 1967.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE	Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 1003, 1973.
rat	LD50	subcutaneous	9800mg/kg (9800mg/kg)		Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 386, 1975.