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5H-Dibenzo[a,d]cycloheptene-5-carboxamide,10,11-dihydro- cas no:7199-29-3

Synonyms: 10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-carboxamide;AY 8682; BS 7029; Carbamazepam; Cyheptamide; ICI 51426

Identification
Name5H-Dibenzo[a,d]cycloheptene-5-carboxamide,10,11-dihydro-
CAS7199-29-3
Synonyms10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-carboxamide;AY 8682; BS 7029; Carbamazepam; Cyheptamide; ICI 51426
EINECS(EC#)230-570-8
Molecular FormulaC16H15 N O
Molecular Weight237.29
Chemical Properties
refractive index1.62
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Moderately toxic by ingestion and intraperitoneal routes. An anticonvulsant. When heated to decomposition it emits toxic fumes of NOx.
Safety Information of Cyheptamide (CAS NO.7199-29-3):
Hazard Codes: Xi
Risk Statements: 36/37/38 
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
Safety Statements: 26-36
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 630mg/kg (630mg/kg)   Journal of Medicinal Chemistry. Vol. 7, Pg. 88, 1964.
mouse LD50 oral 1830mg/kg (1830mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 68, 1972.
rat LD50 intraperitoneal 2gm/kg (2000mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 68, 1972.
rat LD50 oral 2400mg/kg (2400mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 68, 1972.

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