72275-67-3|Astromicin SulfateProducts Supply - Chemical intermediates Network

Astromicin Sulfate cas no:72275-67-3

Synonyms: FortimicinAdisulfate;FortimicinAsulfate;L-chiro-Inositol,4-amino-1-[(aminoacetyl)methylamino]-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-b-L-lyxo-heptopyranosyl)-6-O-methyl-,sulfate

Identification

NameAstromicin Sulfate
CAS72275-67-3
SynonymsFortimicinAdisulfate;FortimicinAsulfate;L-chiro-Inositol,4-amino-1-[(aminoacetyl)methylamino]-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-b-L-lyxo-heptopyranosyl)-6-O-methyl-,sulfate
Molecular FormulaC₁₇H₃₅N₅O₆ . 2H₂O₄S
Molecular Weight601.73

Chemical Properties

refractive index1.585

Safety Data

Safety

Poison by intravenous route. Moderately toxic by intraperitoneal, subcutaneous, and intramuscular routes. Mildly toxic by ingestion. An experimental teratogen. When Fortimicin a sulfate (CAS NO.72275-67-3) is heated to decomposition ,it emits very toxic fumes of SO_x and NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intramuscular	750mg/kg (750mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Chemotherapy Vol. 29(Suppl,
dog	LD50	intravenous	214mg/kg (214mg/kg)		Chemotherapy Vol. 29(Suppl,
guinea pig	LD50	intramuscular	611mg/kg (611mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA	Toxicology and Applied Pharmacology. Vol. 53, Pg. 399, 1980.
mouse	LD50	intramuscular	427mg/kg (427mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA	Chemotherapy Vol. 29(Suppl,
mouse	LD50	intraperitoneal	533mg/kg (533mg/kg)		Chemotherapy Vol. 29(Suppl,
mouse	LD50	intravenous	94mg/kg (94mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA	Toxicology and Applied Pharmacology. Vol. 53, Pg. 399, 1980.
mouse	LD50	oral	13600mg/kg (13600mg/kg)		Chemotherapy Vol. 29(Suppl,
mouse	LD50	subcutaneous	546mg/kg (546mg/kg)		Yakkyoku. Pharmacy. Vol. 36, Pg. 967, 1985.
rabbit	LD50	intravenous	654mg/kg (654mg/kg)		Drugs in Japan Vol. -, Pg. 19, 1995.
rat	LD50	intramuscular	1009mg/kg (1009mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 53, Pg. 399, 1980.
rat	LD50	intraperitoneal	913mg/kg (913mg/kg)		Chemotherapy Vol. 29(Suppl,
rat	LD50	intravenous	86mg/kg (86mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 53, Pg. 399, 1980.
rat	LD50	oral	> 10gm/kg (10000mg/kg)		Chemotherapy Vol. 29(Suppl,
rat	LD50	subcutaneous	1364mg/kg (1364mg/kg)		Chemotherapy Vol. 29(Suppl,

supplier list

Tecoland Corporation: Tel:+1-(732)-603-9577; Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,

Haorui Pharma-Chem Inc.: Tel:+1-(732)-906-7666; Address: 100 Menlo Park Dr, Suite 316, Edison, New Jersey 08837-242,

Hangzhou Dayangchem Co., Ltd.: Tel:86-571-88938639; Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road

Shanghai Fuhe chemistry Technology Co.Ltd.: Tel:86-21-67261018; Address: Room2607,No.1 Building,Lane 519 Aomen Road,Putuo District,Shanghai, China.

Astromicin Sulfate cas no:72275-67-3

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