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Felodipine cas no:72509-76-3

Synonyms: Hydac;Munobal;Plendil;Prevex;Splendil;dl-Felodipine;3,5-Pyridinedicarboxylicacid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester(9CI);Agon;Delmuno;Feloday;Flodil;H 154/82;

Identification
NameFelodipine
CAS72509-76-3
SynonymsHydac;Munobal;Plendil;Prevex;Splendil;dl-Felodipine;3,5-Pyridinedicarboxylicacid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester(9CI);Agon;Delmuno;Feloday;Flodil;H 154/82;
Molecular FormulaC18H19Cl2NO4
Molecular Weight384.26
Chemical Properties
AppearanceWhite or light yellow crystalline powder
storage tempStore in original container in a cool dark place.
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Hazard Codes of?of Felodipine (CAS NO.72509-76-3):?HarmfulXn
Risk Statements: 22
R22: Harmful if swallowed.
Safety Statements: 36
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: US7968700


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 200mg/kg (200mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: NAUSEA OR VOMITING

BLOOD: CHANGES IN SPLEEN
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20, Pg. 2963, 1992.
mouse LD50 intraperitoneal 76mg/kg (76mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
mouse LD50 intravenous 3100ug/kg (3.1mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
mouse LD50 oral 250mg/kg (250mg/kg) ? Cardiovascular Drug Reviews. Vol. 11, Pg. 126, 1993.
mouse LD50 subcutaneous 205mg/kg (205mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
rat LD50 intraperitoneal 23mg/kg (23mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
rat LD50 intravenous 5400ug/kg (5.4mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
rat LD50 oral 1050mg/kg (1050mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
rat LD50 subcutaneous > 600mg/kg (600mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.

supplier list

Haining Zhonglian Chemical Co., Ltd.
Tel:+86-(573)-8796-6889, +86-13567318202
Address: Haining Foreign Comprehensive Development Zone, Lingtaolu, Zhejiang 314423,
Vesino Industrial Co., Ltd.
Tel:86-22-27455635
Address: No.4 Xinglanyuan Building, Changjiang Road, Tianjin 300193,
Leawell International Limited
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Address: 18/F Catic Plaza, 8 Causeway Road Causeway Bay,
Tocris Bioscience
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Yingxuan Chempharm Co., Ltd.
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Address: Rm.1705, No.51, JinZang Rd., Pudong, Shanghai 201206,
Wuhan Pharma Chemical Co., Ltd.
Tel:+86-27-87711369
Address: 430071
Weistar Industry Limited
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Address: 8th Floor, Meixin Business Building, No.820 Fenghuang Road, Huzhou, Zhejiang 313000,
ACIC Fine Chemicals Inc.
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Address: 11772 West Sample Road, Coral Springs, Florida 33065,
Ningbo Yuanfang Biochemicals Co., Ltd.
Tel:+86-(574)-2786-2437, 2786-2438
Address:
Facus Pharmaceutical Co., Ltd.
Tel:+86-(574)-6237-8411
Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800,
Yuyang Of Chengdu High-tech Development Co., Ltd.
Tel:+86-(28)-87573825
Address: Chengdu Golden Housing Court Hengjie 8 # 4-2-9, Chengdu, Sichuan,
Zhejiang Wonderful Pharma & Chem Co.
Tel:
Address:
Tianjin Hi-Tesion Bio&Chem Co., Ltd.
Tel:+86-(22)-2372-5099
Address: C1506, Wanhao Mansion, No.333 Binshuixi Road, Nankai District, Tianjin 300381,
Rota Pharm & Chem Co., Ltd.
Tel:+86-(571)-8836-9502
Address: Room 401,Hangzhou Friendship Plaza,No.74 Bbaochu Road, Hangzhou, Zhejiang,
Wujin Hengfeng Chemical Plant
Tel:+86-(519)-88615566
Address: Zouqu Town, Wujing Distrct, Changzhou, Jiangsu 213144,

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