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Felodipine cas no:72509-76-3

Synonyms: Hydac;Munobal;Plendil;Prevex;Splendil;dl-Felodipine;3,5-Pyridinedicarboxylicacid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester(9CI);Agon;Delmuno;Feloday;Flodil;H 154/82;

Identification
NameFelodipine
CAS72509-76-3
SynonymsHydac;Munobal;Plendil;Prevex;Splendil;dl-Felodipine;3,5-Pyridinedicarboxylicacid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester(9CI);Agon;Delmuno;Feloday;Flodil;H 154/82;
Molecular FormulaC18H19Cl2NO4
Molecular Weight384.26
Chemical Properties
AppearanceWhite or light yellow crystalline powder
storage tempStore in original container in a cool dark place.
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Hazard Codes of?of Felodipine (CAS NO.72509-76-3):?HarmfulXn
Risk Statements: 22
R22: Harmful if swallowed.
Safety Statements: 36
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: US7968700


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo oral 200mg/kg (200mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: NAUSEA OR VOMITING

BLOOD: CHANGES IN SPLEEN
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20, Pg. 2963, 1992.
mouse LD50 intraperitoneal 76mg/kg (76mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
mouse LD50 intravenous 3100ug/kg (3.1mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
mouse LD50 oral 250mg/kg (250mg/kg) ? Cardiovascular Drug Reviews. Vol. 11, Pg. 126, 1993.
mouse LD50 subcutaneous 205mg/kg (205mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
rat LD50 intraperitoneal 23mg/kg (23mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
rat LD50 intravenous 5400ug/kg (5.4mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
rat LD50 oral 1050mg/kg (1050mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.
rat LD50 subcutaneous > 600mg/kg (600mg/kg) ? Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 26, Pg. 239, 1995.

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Haining Zhonglian Chemical Co., Ltd.
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Pharmasolve Specialities (I) PVT. LTD.
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Ningbo Yuanfang Biochemicals Co., Ltd.
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SNC International Co., Ltd.
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Hangzhou Lanpharma Co., Ltd.
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Fujian Pucheng Medicine Chemical Industry Co.,ltd
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Address: Fine chemical Industry area,linjiang town,Pucheng county,Fujian,China
Hangzhou Shilian Medicine Chemical Co., Ltd
Tel:+86-571-88228154
Address: Rm. 305, 130# of Tiyuchang Rd., Hangzhou City, Zhejiang

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