Prometryn (N,N'-Bis(1-methylethyl)-6-methylthio-1,3,5- triazine-2,4-diamine) cas no:7287-19-6

NamePrometryn (N,N'-Bis(1-methylethyl)-6-methylthio-1,3,5- triazine-2,4-diamine)
CAS7287-19-6
Synonyms1,3,5-Triazine-2,4-diamine,N,N'-bis(1-methylethyl)-6-(methylthio)- (9CI); s-Triazine, 2,4-bis(isopropylamino)-6-(methylthio)-(6CI,8CI); 2,4-Bis(isopropylamino)-6-(methylthio)-s-triazine;2,4-Bis(isopropylamino)-6-methylmercapto-s-triazine;2-(Methylthio)-4,6-diisopropylamino-1,3,5-triazine;2-Methylmercapto-4,6-bis(isopropylamino)-1,3,5-triazine;2-Methylmercapto-4,6-bis(isopropylamino)-s-triazine;2-Methylthio-4,6-bis(isopropylamino)-1,3,5-triazine;2-Methylthio-4,6-bis(isopropylamino)-s-triazine;2-Methylthio-4,6-bis(isopropylamino)-sym-triazine;4,6-Bis(isopropylamino)-2-(methylthio)-1,3,5-triazine;4,6-Bis(isopropylamino)-2-(methylthio)-s-triazine; A 1114; Azogard; Caparol;Cosatrin; Cotogard; G 34161; Gesagard; Gesagard 50; Mercazin;N,N'-Bis(1-methylethyl)-6-methylthio-1,3,5-triazine-2,4-diamine; NSC 163049;Prohelan; Promepin; Prometrex; Prometrin S 50; Prometryn; Prometryne; Selectin;Selectin (herbicide); Selectin 50; Selektin; Uvon
EINECS(EC#)230-711-3
Molecular FormulaC10H19 N5 S
Molecular Weight241.35

AppearanceColorless crystals
storage tempAPPROX 4°C

Hazard F,Xn,N
Risk R11
Safety Moderately toxic by ingestion. Experimental reproductive effects. An eye irritant. Mutation data reported. An herbicide. When heated to decomposition it emits very toxic fumes of NOx and SOx. See also MERCAPTANS.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

XY4390000

CHEMICAL NAME :

s-Triazine, 2,4-bis(isopropylamino)-6-(methylthio)-

CAS REGISTRY NUMBER :

7287-19-6

LAST UPDATED :

199710

DATA ITEMS CITED :

15

MOLECULAR FORMULA :

C10-H19-N5-S

MOLECULAR WEIGHT :

241.40

WISWESSER LINE NOTATION :

T6N CN ENJ BS1 DMY1&1 FMY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

Standard Draize test

ROUTE OF EXPOSURE :

Administration into the eye

SPECIES OBSERVED :

Rodent - rabbit

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2100 mg/kg

TOXIC EFFECTS :

Autonomic Nervous System - other (direct) parasympathomimetic Lungs, Thorax, or Respiration - other changes Gastrointestinal - other changes

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>2430 mg/m3/4H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>3100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2138 mg/kg

TOXIC EFFECTS :

Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Kidney, Ureter, Bladder - urine volume increased

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - rabbit

DOSE/DURATION :

>3100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Unreported

SPECIES OBSERVED :

Mammal - species unspecified

DOSE/DURATION :

1800 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

14223 mg/kg/7W-I

TOXIC EFFECTS :

Liver - changes in liver weight Endocrine - changes in adrenal weight Blood - other changes

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

2400 mg/kg

SEX/DURATION :

female 18-20 day(s) after conception lactating female 2-4 day(s) post-birth

TOXIC EFFECTS :

Reproductive - Effects on Newborn - behavioral Reproductive - Effects on Newborn - physical Reproductive - Effects on Newborn - delayed effects

MUTATION DATA

TYPE OF TEST :

Gene conversion and mitotic recombination

TEST SYSTEM :

Yeast - Saccharomyces cerevisiae

DOSE/DURATION :

500 ug/L

REFERENCE :

CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 21(2),59,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3180 No. of Facilities: 167 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1169 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3180 No. of Facilities: 13 (estimated) No. of Industries: 1 No. of Occupations: 9 No. of Employees: 567 (estimated) No. of Female Employees: 13 (estimated)