73-22-3|L-TryptophanProducts Supply - Chemical intermediates Network

L-Tryptophan cas no:73-22-3

Synonyms: L(-)-Tryptophan;EH 121;l-alpha-Aminoindole-3-propionic acid;(S)-alpha-Amino-beta-(3-indolyl)-propionic acid;Sedanoct;L-Tryptophan (JP14);L-Trp;(S)-alpha-Amino-beta-indolepropionic acid;NCI-C01729;(S)-2-Amino-3-(3-indolyl)propionic acid;(-)-Tryptophan;(S)-alpha-Aminoindole-3-propionic acid;(2S)-2-azaniumyl-3-(1H-indol-3-yl)propanoate;Tryptophan, L-;2-Amino-3-indolylpropanoic acid;WV;Pacitron;Indole-3-alanine;1H-Indole-3-propanoic acid, alpha-amino-, (S)-;(S)-Tryptophan;Alanine, 3-indol-3-yl;L-(-)-Tryptophan;Triptofano [Spanish];3-Indol-3-ylalanine;Ardeytropin;L-alpha-Amino-3-indolepropionic acid;(S)-alpha-Amino-1H-indole-3-propanoic acid;Tryptophan (VAN);alpha-Amino-3-indolepropionic acid, L-;Tryptophanum [Latin];L-Alanine, 3-(1H-indol-3-yl)-;L-Tryptophan (9CI);

Identification

NameL-Tryptophan
CAS73-22-3
SynonymsL(-)-Tryptophan;EH 121;l-alpha-Aminoindole-3-propionic acid;(S)-alpha-Amino-beta-(3-indolyl)-propionic acid;Sedanoct;L-Tryptophan (JP14);L-Trp;(S)-alpha-Amino-beta-indolepropionic acid;NCI-C01729;(S)-2-Amino-3-(3-indolyl)propionic acid;(-)-Tryptophan;(S)-alpha-Aminoindole-3-propionic acid;(2S)-2-azaniumyl-3-(1H-indol-3-yl)propanoate;Tryptophan, L-;2-Amino-3-indolylpropanoic acid;WV;Pacitron;Indole-3-alanine;1H-Indole-3-propanoic acid, alpha-amino-, (S)-;(S)-Tryptophan;Alanine, 3-indol-3-yl;L-(-)-Tryptophan;Triptofano [Spanish];3-Indol-3-ylalanine;Ardeytropin;L-alpha-Amino-3-indolepropionic acid;(S)-alpha-Amino-1H-indole-3-propanoic acid;Tryptophan (VAN);alpha-Amino-3-indolepropionic acid, L-;Tryptophanum [Latin];L-Alanine, 3-(1H-indol-3-yl)-;L-Tryptophan (9CI);
EINECS(EC#)200-795-6
Molecular FormulaC₁₁H₁₂N₂O₂
Molecular Weight204.23

Chemical Properties

AppearanceWhite to off-white crystalline powder
alpha-31.1 o (C=1, H20)
refractive index-32 ° (C=1, H2O)
storage tempStore at RT.

Safety Data

Hazard Xi: Irritant;
Risk R33;R40
Safety

Moderately toxic by intraperitoneal route. Experimental teratogenic and reproductive effects. Human mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes?of L-Tryptophan (CAS NO.73-22-3):?Xi
Risk Statements: 33-40-62-41-37/38-36/37/38-22
R33: Danger of cumulative effects.?
R40: Limited evidence of a carcinogenic effect.?
R62: Risk of impaired fertility.?
R41: Risk of serious damage to the eyes.?
R37/38: Irritating to respiratory system and skin.?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R22: Harmful if swallowed.
Safety Statements: 24/25-36/37/39-36-26
S24/25: Avoid contact with skin and eyes.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S36: Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: YN6130000
F: 8
HS Code: 29339990

HS Code 29339990

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - domestic	LD50	intraperitoneal	2410mg/kg (2410mg/kg)	?	Drugs in Japan Vol. -, Pg. 744, 1990.
man	TDLo	oral	300mg/kg (300mg/kg)	BEHAVIORAL: EXCITEMENT BEHAVIORAL: ANTIANXIETY	British Medical Journal. Vol. 2, Pg. 701, 1976.
man	TDLo	oral	857mg/kg/30D- (857mg/kg)	BLOOD: EOSINOPHILIA SKIN AND APPENDAGES (SKIN): OTHER GLANDS: OTHER MUSCULOSKELETAL: OTHER CHANGES	New England Journal of Medicine. Vol. 322, Pg. 874, 1990.
mouse	LD50	intraperitoneal	4800mg/kg (4800mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 635, 1980.
mouse	LDLo	oral	15gm/kg (15000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 635, 1980.
rat	LD50	intraperitoneal	1634mg/kg (1634mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives of Biochemistry and Biophysics. Vol. 58, Pg. 253, 1955.
rat	LD50	oral	> 16gm/kg (16000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: COMA	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 11, Pg. 635, 1980.
rat	LDLo	unreported	2553mg/kg (2553mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 884, 1973.
women	TDLo	oral	2700mg/kg/13W (2700mg/kg)	LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA BLOOD: EOSINOPHILIA	Annals of Internal Medicine. Vol. 112, Pg. 301, 1990.
women	TDLo	oral	3276mg/kg/9W- (3276mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BLOOD: EOSINOPHILIA SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Annals of Internal Medicine. Vol. 112, Pg. 344, 1990.
women	TDLo	oral	4800mg/kg/34W (4800mg/kg)	PERIPHERAL NERVE AND SENSATION: PARESTHESIS SKIN AND APPENDAGES (SKIN): OTHER GLANDS: OTHER BLOOD: EOSINOPHILIA	New England Journal of Medicine. Vol. 322, Pg. 874, 1990.
women	TDLo	oral	5400mg/kg/134 (5400mg/kg)	BLOOD: EOSINOPHILIA SKIN AND APPENDAGES (SKIN): OTHER GLANDS: OTHER	New England Journal of Medicine. Vol. 322, Pg. 874, 1990.
women	TDLo	oral	9gm/kg/22W-I (9000mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS LIVER: LIVER FUNCTION TESTS IMPAIRED BLOOD: EOSINOPHILIA	Annals of Internal Medicine. Vol. 112, Pg. 957, 1990.
women	TDLo	oral	10960mg/kg/20 (10960mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA BLOOD: EOSINOPHILIA	British Medical Journal. Vol. 301, Pg. 21, 1990.

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L-Tryptophan cas no:73-22-3

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