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Adenine cas no:73-24-5

Synonyms: 1H-Purin-6-amine; 6-Aminopurine; A; Ade; Adeninimine; Vitamin B4;

Identification
NameAdenine
CAS73-24-5
Synonyms1H-Purin-6-amine; 6-Aminopurine; A; Ade; Adeninimine; Vitamin B4;
EINECS(EC#)200-796-1
Molecular FormulaC5H5N5
Molecular Weight135.13
Chemical Properties
Appearancewhite to off-white crystalline powder
refractive index1.954
storage tempStore at RT.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard Xn:Harmful
Risk R22
Safety

Hazard Codes:?Xn,Xi
Risk Statements: 22-20/21/22?
R22:Harmful if swallowed.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: AU6125000
HazardClass: 6.1
PackingGroup: III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 100mg/kg (100mg/kg) ? National Technical Information Service. Vol. AD277-689,
mouse LD50 intravenous > 30mg/kg (30mg/kg) ? Drugs in Japan Vol. 6, Pg. 20, 1982.
mouse LD50 oral 783mg/kg (783mg/kg) ? Drugs in Japan Vol. 6, Pg. 19, 1982.
mouse LDLo subcutaneous 1gm/kg (1000mg/kg) ? Annals of the New York Academy of Sciences. Vol. 60, Pg. 251, 1954.
rat LD50 intraperitoneal 198mg/kg (198mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Journal of Pharmacology and Experimental Therapeutics. Vol. 104, Pg. 20, 1952.
rat LD50 oral 227mg/kg (227mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Toxicology and Applied Pharmacology. Vol. 47, Pg. 229, 1979.

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