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Melatonine cas no:73-31-4

Synonyms: N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide;N-Acetyl-5-methoxytryptamine;5-Methoxy-N-acetyltryptamine;Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-;acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-;N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide;Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI);Melovine;Acetamide, N-[2- (5-methoxy-1H-indol-3-yl)ethyl]-;Melatonin;Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-};Circadin;Acetamide,N-[2-(5-methoxy-1H-indol-3-yl)- ethyl]-;Prestwick_312;Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI);Melatonin (MLT);

Identification
NameMelatonine
CAS73-31-4
SynonymsN-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide;N-Acetyl-5-methoxytryptamine;5-Methoxy-N-acetyltryptamine;Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-;acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-;N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide;Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI);Melovine;Acetamide, N-[2- (5-methoxy-1H-indol-3-yl)ethyl]-;Melatonin;Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-};Circadin;Acetamide,N-[2-(5-methoxy-1H-indol-3-yl)- ethyl]-;Prestwick_312;Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI);Melatonin (MLT);
EINECS(EC#)200-797-7
Molecular FormulaC13H16N2O2
Molecular Weight232.31 g/mol
Chemical Properties
AppearanceWhite crystalline powder
storage temp-15°C
Safety Data

Hazard T: Toxic;
Risk R60
Safety

Hazard Codes:?ToxicT?
Risk Statements: 60?
R60: May impair fertility.
Safety Statements: 24/25
S24/25: Avoid contact with skin and eyes.?
WGK Germany: 2?
RTECS: AC5955000
F: 8-10-23


HS Code 29379000

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1375mg/kg (1375mg/kg) ? Pharmaceutical Chemistry Journal Vol. 17, Pg. 559, 1983.
mouse LD50 intravenous 180mg/kg (180mg/kg) ? U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02739,
mouse LD50 oral 1250mg/kg (1250mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
mouse LD50 subcutaneous > 1600mg/kg (1600mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
rat LD50 intraperitoneal 1131mg/kg (1131mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
rat LD50 intravenous 356mg/kg (356mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
rat LD50 oral > 3200mg/kg (3200mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
rat LD50 subcutaneous > 1600mg/kg (1600mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.

?Melatonin (CAS NO.73-31-4) has a very low toxicity in rats. Rat maternal toxicity: the no observable adverse effect level (NOAEL) and lowest observed adverse effect level (LOAEL) were 100 and 200 mg/kg/day, respectively, and the developmental toxicity NOAEL was >= 200 mg/kg/day.

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Huangshi Sinon Chemistry Technology Co.,Ltd.
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Xian Chukang Biotechnology Co., Ltd.
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