73-31-4|MelatonineProducts Supply - Chemical intermediates Network

Melatonine cas no:73-31-4

Synonyms: N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide;N-Acetyl-5-methoxytryptamine;5-Methoxy-N-acetyltryptamine;Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-;acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-;N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide;Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI);Melovine;Acetamide, N-[2- (5-methoxy-1H-indol-3-yl)ethyl]-;Melatonin;Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-};Circadin;Acetamide,N-[2-(5-methoxy-1H-indol-3-yl)- ethyl]-;Prestwick_312;Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI);Melatonin (MLT);

Identification

NameMelatonine
CAS73-31-4
SynonymsN-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide;N-Acetyl-5-methoxytryptamine;5-Methoxy-N-acetyltryptamine;Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-;acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-;N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide;Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI);Melovine;Acetamide, N-[2- (5-methoxy-1H-indol-3-yl)ethyl]-;Melatonin;Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-};Circadin;Acetamide,N-[2-(5-methoxy-1H-indol-3-yl)- ethyl]-;Prestwick_312;Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI);Melatonin (MLT);
EINECS(EC#)200-797-7
Molecular FormulaC₁₃H₁₆N₂O₂
Molecular Weight232.31 g/mol

Chemical Properties

AppearanceWhite crystalline powder
storage temp-15°C

Safety Data

Hazard T: Toxic;
Risk R60
Safety

Hazard Codes:? Toxic T?
Risk Statements: 60?
R60: May impair fertility.
Safety Statements: 24/25
S24/25: Avoid contact with skin and eyes.?
WGK Germany: 2?
RTECS: AC5955000
F: 8-10-23

HS Code 29379000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	1375mg/kg (1375mg/kg)	?	Pharmaceutical Chemistry Journal Vol. 17, Pg. 559, 1983.
mouse	LD50	intravenous	180mg/kg (180mg/kg)	?	U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02739,
mouse	LD50	oral	1250mg/kg (1250mg/kg)	?	Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
mouse	LD50	subcutaneous	> 1600mg/kg (1600mg/kg)	?	Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
rat	LD50	intraperitoneal	1131mg/kg (1131mg/kg)	?	Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
rat	LD50	intravenous	356mg/kg (356mg/kg)	?	Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
rat	LD50	oral	> 3200mg/kg (3200mg/kg)	?	Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.
rat	LD50	subcutaneous	> 1600mg/kg (1600mg/kg)	?	Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983.

?Melatonin (CAS NO.73-31-4) has a very low toxicity in rats. Rat maternal toxicity: the no observable adverse effect level (NOAEL) and lowest observed adverse effect level (LOAEL) were 100 and 200 mg/kg/day, respectively, and the developmental toxicity NOAEL was >= 200 mg/kg/day.

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Melatonine cas no:73-31-4

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