Melatonine  cas no:73-31-4
         
           
           Synonyms:  N-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide;N-Acetyl-5-methoxytryptamine;5-Methoxy-N-acetyltryptamine;Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-;acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-;N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide;Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI);Melovine;Acetamide, N-[2- (5-methoxy-1H-indol-3-yl)ethyl]-;Melatonin;Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-};Circadin;Acetamide,N-[2-(5-methoxy-1H-indol-3-yl)- ethyl]-;Prestwick_312;Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI);Melatonin (MLT);
           
           
           
            
      
         
          
          NameMelatonine 
            CAS73-31-4 
            SynonymsN-(2-(5-Methoxy-1H-indol-3-yl)ethyl)acetamide;N-Acetyl-5-methoxytryptamine;5-Methoxy-N-acetyltryptamine;Acetamide, N-(2-(5-methoxyindol-3-yl)ethyl)-;acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-;N-(2-(5-Methoxyindol-3-yl)ethyl)acetamide;Acetamide, N-[2-(5-methoxyindol-3-yl)ethyl]- (6CI,8CI);Melovine;Acetamide, N-[2- (5-methoxy-1H-indol-3-yl)ethyl]-;Melatonin;Acetamide, {N-[2-(5-methoxyindol-3-yl)ethyl]-};Circadin;Acetamide,N-[2-(5-methoxy-1H-indol-3-yl)- ethyl]-;Prestwick_312;Acetamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]- (9CI);Melatonin (MLT);
            EINECS(EC#)200-797-7 
            Molecular FormulaC13H16N2O2
            
            Molecular Weight232.31 g/mol 
            
            
         
          
            AppearanceWhite crystalline powder 
            
            
            
            storage temp-15°C 
            
            
            
            
          
          
          
            Hazard T: Toxic; 
              Risk R60
              Safety     
        
    
    
        
Hazard Codes:? T?
T?
        Risk Statements: 60?
        R60: May impair fertility. 
        Safety Statements: 24/25
        S24/25: Avoid contact with skin and eyes.?
        WGK Germany: 2?
        RTECS: AC5955000
        F: 8-10-23
    
              
              
              
              
              HS Code 29379000 
                    
      
 
      
          
                
        
    
    
        
        
            
                
                    | Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source | 
            
            
                
                    | mouse | LD50 | intraperitoneal | 1375mg/kg (1375mg/kg) | ? | Pharmaceutical Chemistry Journal Vol. 17, Pg. 559, 1983. | 
                
                    | mouse | LD50 | intravenous | 180mg/kg (180mg/kg) | ? | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02739, | 
                
                    | mouse | LD50 | oral | 1250mg/kg (1250mg/kg) | ? | Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983. | 
                
                    | mouse | LD50 | subcutaneous | > 1600mg/kg (1600mg/kg) | ? | Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983. | 
                
                    | rat | LD50 | intraperitoneal | 1131mg/kg (1131mg/kg) | ? | Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983. | 
                
                    | rat | LD50 | intravenous | 356mg/kg (356mg/kg) | ? | Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983. | 
                
                    | rat | LD50 | oral | > 3200mg/kg (3200mg/kg) | ? | Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983. | 
                
                    | rat | LD50 | subcutaneous | > 1600mg/kg (1600mg/kg) | ? | Journal of Pharmacology and Experimental Therapeutics. Vol. 227, Pg. 587, 1983. | 
            
        
        
        ?Melatonin (CAS NO.73-31-4) has a very low toxicity in rats. Rat maternal toxicity: the no observable adverse effect level (NOAEL) and lowest observed adverse effect level (LOAEL) were 100 and 200 mg/kg/day, respectively, and the developmental toxicity NOAEL was >= 200 mg/kg/day.