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lidocaine hydrochloride cas no:73-78-9

Synonyms: 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide hydrochloride; Lidocaine HCl; Lignocaine HCl; lidocaineHydrochloride

Identification
Namelidocaine hydrochloride
CAS73-78-9
Synonyms2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide hydrochloride; Lidocaine HCl; Lignocaine HCl; lidocaineHydrochloride
EINECS(EC#)200-803-8
Molecular FormulaC14H22N2O?HCl
Molecular Weight234.33728
Chemical Properties
AppearanceWhite crystal powder
storage tempRefrigerator
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Safety

Poison by ingestion, intraperitoneal, intravenous, subcutaneous, intramuscular, and intratracheal routes. Human systemic effects: somnolence, respiratory depression, low blood pressure, cardiomyopathy including infarction, pulse rate increase. An experimental teratogen. Other experimental reproductive effects. A skin and eye irritant. An anesthetic. When heated to decomposition it emits very toic fumes of NOx and HCl.?Its hazard class?is 6.1(b).
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1. ???

skn-rbt 3% MLD

??? AIPTAK ?? Archives Internationales de Pharmacodynamie et de Therapie. 137 (1962),410.
2. ???

eye-rbt 3% MLD

??? AIPTAK ?? Archives Internationales de Pharmacodynamie et de Therapie. 137 (1962),410.
3. ???

ivn-cld TDLo:60?mg/kg/1H

??? JTCTDW ?? Journal of Toxicology, Clinical Toxicology. 24 (1986),51.
4. ???

ivn-man TDLo:9?mg/kg/4H-C:CVS

??? DICPBB ?? Drug Intelligence and Clinical Pharmacy. 19 (1985),669.
5. ???

ivn-man TDLo:7143?μg/kg:BPR

??? CHETBF ?? Chest: The Journal of Circulation, Respiration and Related Systems. 61 (1972),682.
6. ???

imp-man TDLo:5714?μg/kg

??? CMAJAX ?? Canadian Medical Association Journal. 137 (1987),219.
7. ???

ipr-rat LD50:122?mg/kg

??? JPETAB ?? Journal of Pharmacology and Experimental Therapeutics. 111 (1954),224.
8. ???

scu-rat LD50:570?mg/kg

??? RPOBAR ?? Research Progress in Organic Biological and Medicinal Chemistry. 2 (1970),299.
9. ???

ivn-rat LD50:21?mg/kg

??? RPOBAR ?? Research Progress in Organic Biological and Medicinal Chemistry. 2 (1970),299.
10. ???

orl-mus LD50:220?mg/kg

??? RPOBAR &nbs

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Saniver Limited
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