Mevastatin cas no:73573-88-3
Synonyms: Butanoicacid, 2-methyl-,(1S,7S,8S,8αR)-1,2,3,7,8,8α-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenylester, (2S)-;Butanoicacid, 2-methyl-,1,2,3,7,8,8α-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenylester, [1S-[1α(R*),7b,8b(2S*,4S*),8ab]]-;Antibiotic ML 236B;CS 500;CS 500(antibiotic);Compactin;Compactin (Penicillium);L 637312;ML 236B;ML 236Blactone;NSC 281245;Statin I;
NameMevastatin
CAS73573-88-3
SynonymsButanoicacid, 2-methyl-,(1S,7S,8S,8αR)-1,2,3,7,8,8α-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenylester, (2S)-;Butanoicacid, 2-methyl-,1,2,3,7,8,8α-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenylester, [1S-[1α(R*),7b,8b(2S*,4S*),8ab]]-;Antibiotic ML 236B;CS 500;CS 500(antibiotic);Compactin;Compactin (Penicillium);L 637312;ML 236B;ML 236Blactone;NSC 281245;Statin I;
Molecular FormulaC23H34O5
Molecular Weight390.51306
Appearancewhite powder
refractive index1.528
storage temp2-8°C
Hazard T+
Risk R26/27/28
Safety Hazard Codes:T+
Risk Statements:26/27/28
26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed
Safety Statements:22-24/25-45-36/37/39
22:Do not breathe dust
24/25:Avoid contact with skin and eyes
45:In case of accident or if you feel unwell, seek medical
advice immediately (show label where possible)
36/37/39:Wear suitable protective clothing, gloves and eye/face
protection
WGK Germany:3
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EK7907100
- CHEMICAL NAME :
- Butanoic acid, 2-methyl-,
1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hy
droxy-6-oxo-2H-pyran- 2-yl)ethyl)-1-naphthalenyl
ester,
(1S-(1-alpha(R*),7-beta,8-beta(2S*,4S*),8a-beta))-
- CAS REGISTRY NUMBER :
- 73573-88-3
- LAST UPDATED :
- 199212
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C23-H34-O5
- MOLECULAR WEIGHT :
- 390.57
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 29,1346,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8
Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968-
Volume(issue)/page/year: 29,1346,1976
