Benzamide,3-(aminosulfonyl)-4-chloro-N-[(3aR,4R,7S,7aS)-octahydro-4,7-methano-2H-isoindol-2-yl]-,rel- cas no:73803-48-2

NameBenzamide,3-(aminosulfonyl)-4-chloro-N-[(3aR,4R,7S,7aS)-octahydro-4,7-methano-2H-isoindol-2-yl]-,rel-
CAS73803-48-2
SynonymsBenzamide,3-(aminosulfonyl)-4-chloro-N-(octahydro-4,7-methano-2H-isoindol-2-yl)-, (3aa,4a,7a,7aa)-; 4,7-Methano-2H-isoindole,benzamide deriv.; ADR 033; E 614; Normonal; TDS; TDS (diuretic); Toripamide;Tripamide
Molecular FormulaC16H20 Cl N3 O3 S
Molecular Weight0

refractive index1.673

Safety

An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of Cl⁻, SO_x and NO_x.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 2gm/kg (2000mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.
mouse	LD50	intramuscular	> 2500mg/kg (2500mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.
mouse	LD50	intraperitoneal	> 5gm/kg (5000mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.
mouse	LD50	oral	> 5gm/kg (5000mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.
mouse	LD50	subcutaneous	> 2500mg/kg (2500mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.
rat	LD50	intramuscular	> 2gm/kg (2000mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.
rat	LD50	intraperitoneal	> 4gm/kg (4000mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.
rat	LD50	oral	> 8gm/kg (8000mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.
rat	LD50	subcutaneous	> 2gm/kg (2000mg/kg)		Drugs in Japan Vol. 6, Pg. APP-15, 1982.