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5H-Dibenz[b,f]azepine-5-propanamine,10,11-dihydro-N,N,b-trimethyl- cas no:739-71-9

Synonyms: 5H-Dibenz[b,f]azepine,5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro- (6CI,7CI,8CI); (?à)-Trimipramine;10,11-Dihydro-5-(3-dimethylamino-2-methylpropyl)-5H-dibenz[b,f]azepine; 5-(g-Dimethylamino-b-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine;5-[3-(Dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine; 7162RP; IL 6001; RP 7162; Rhotrimine; Sapilent; Surmontil; Trimeprimine;Trimeproprimine; Trimipramine; b-Methylimipramine

Identification
Name5H-Dibenz[b,f]azepine-5-propanamine,10,11-dihydro-N,N,b-trimethyl-
CAS739-71-9
Synonyms5H-Dibenz[b,f]azepine,5-[3-(dimethylamino)-2-methylpropyl]-10,11-dihydro- (6CI,7CI,8CI); (?à)-Trimipramine;10,11-Dihydro-5-(3-dimethylamino-2-methylpropyl)-5H-dibenz[b,f]azepine; 5-(g-Dimethylamino-b-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine;5-[3-(Dimethylamino)-2-methylpropyl]-10,11-dihydro-5H-dibenz[b,f]azepine; 7162RP; IL 6001; RP 7162; Rhotrimine; Sapilent; Surmontil; Trimeprimine;Trimeproprimine; Trimipramine; b-Methylimipramine
EINECS(EC#)212-008-3
Molecular FormulaC20H26 N2
Molecular Weight294.48
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Safety

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by ingestion: unspecified heart effects. When heated to decomposition it emits toxic fumes of NOx.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III


Toxicity
1.    

orl-hmn TDLo:18 mg/kg:CVS

    PSDTAP    Proceedings of the European Society for the Study of Drug Toxicity. 6 (1965),171.
2.    

orl-mus LD50:250 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 102 (1963),753.
3.    

ipr-mus LD50:145 mg/kg

    CRSBAW    Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. 155 (1961),307.
4.    

scu-mus LD50:200 mg/kg

    BCFAAI    Bollettino Chimico Farmaceutico. 102 (1963),753.
5.    

ivn-mus LD50:42 mg/kg

    CRSBAW    Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. 155 (1961),307.

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