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Methane, chloro- cas no:74-87-3

Synonyms: chloromethane;

Identification
NameMethane, chloro-
CAS74-87-3
Synonymschloromethane;
EINECS(EC#)200-817-4
Molecular FormulaCH3Cl
Molecular Weight50.4872
Chemical Properties
Appearancecolourless gas
refractive index1.0007
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass2.1
Safety Data

Hazard Flammable, dangerous fire risk, explosive limits in air 10.7–17%. Narcotic. Psychic effects. TLV: TWA 50 ppm; STEL 100 ppm; not classifiable as a human carcinogen.
Risk R12
Safety

Hazard Codes of?Methyl chloride (CAS NO.74-87-3):?F+,Xn,T,F
Risk Statements: 12-40-48/20-67-66-22-19-38-23/25-11?
R12:Extremely flammable.?
R40:Limited evidence of a carcinogenic effect.?
R48:Danger of serious damage to health by prolonged exposure.?
R20:Harmful by inhalation.?
R67:Vapours may cause drowsiness and dizziness.?
R66:Repeated exposure may cause skin dryness or cracking.?
R22:Harmful if swallowed.?
R19:May form explosive peroxides.?
R38:Irritating to skin.?
R23/25:Toxic by inhalation and if swallowed.?
R11:Highly flammable.
Safety Statements: 9-16-33-29-36-24-45-7?
S9:Keep container in a well-ventilated place.?
S16:Keep away from sources of ignition.?
S33:Take precautionary measures against static discharges.?
S29:Do not empty into drains.?
S36:Wear suitable protective clothing.?
S24:Avoid contact with skin.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S7:Keep container tightly closed.
RIDADR: UN 1993 3/PG 1
WGK Germany: 2
RTECS: PA6300000
HazardClass: 2.1


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 129mg/m3/4H (129mg/m3) BEHAVIORAL: GENERAL ANESTHETIC

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Archiv fuer Hygiene und Bakteriologie. Vol. 116, Pg. 131, 1936.
dog LCLo inhalation 14661ppm/6H (14661ppm) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
National Institutes of Health, Bulletin. Vol. 191, Pg. 1, 1949.
guinea pig LCLo inhalation 20000ppm/2H (20000ppm) ? Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967.
human LCLo inhalation 20000ppm/2H (20000ppm) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: NAUSEA OR VOMITING
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 386, 1969.
mouse LC50 inhalation 2200ppm/6H (2200ppm) ? Toxicology and Applied Pharmacology. Vol. 86, Pg. 93, 1986.
rat LC50 inhalation 5300mg/m3/4H (5300mg/m3) ? "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 82, 1982.
rat LD50 oral 1800mg/kg (1800mg/kg) ? "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 86, 1986.

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