74011-58-8|EnoxacinProducts Supply - Chemical intermediates Network

Enoxacin cas no:74011-58-8

Synonyms: 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylicacid;AT 2266;CI 919;ENOXOR;Enofloxacin;Enofloxacine;Enoksetin;Enoxacine;Flumark;1,8-Naphthyridine-3-carboxylicacid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-;Penetrex;Penetrex (pharmaceutical);

Identification

NameEnoxacin
CAS74011-58-8
Synonyms1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylicacid;AT 2266;CI 919;ENOXOR;Enofloxacin;Enofloxacine;Enoksetin;Enoxacine;Flumark;1,8-Naphthyridine-3-carboxylicacid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-;Penetrex;Penetrex (pharmaceutical);
Molecular FormulaC₁₅H₁₇FN₄O₃
Molecular Weight320.318883

Chemical Properties

Appearanceoff-white to yellow crystals
storage temp2-8°C

Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:? Irritant Xi
Risk Statements: 36/37/38?
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37: Wear suitable protective clothing and gloves.
WGK Germany: 2
RTECS of Enoxacin (CAS NO.74011-58-8): QN2800000

HS Code 29335995

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 1600mg/kg (1600mg/kg)	BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 32(Suppl,
monkey	LD50	oral	> 1600mg/kg (1600mg/kg)	BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 32(Suppl,
mouse	LD50	intraperitoneal	3600mg/kg (3600mg/kg)	?	Ensho. Japanese Journal of Inflammation. Vol. 11, Pg. 343, 1991.
mouse	LD50	intravenous	327mg/kg (327mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Chemotherapy Vol. 32(Suppl,
mouse	LD50	oral	> 4gm/kg (4000mg/kg)	?	European Patent Application. Vol. #0009425,
mouse	LD50	subcutaneous	1100mg/kg (1100mg/kg)	?	"Current Chemotherapy and Infectious Diseases, Proceedings of the 11th International Congress of Chemotherapy and the 19th Interscience Conference on Antimicrobial Agents and Chemotherapy, Boston, MA, 1979," Washington, DC, American Soc. for Microbiology, 1980Vol. 1, Pg. 456, 1980.
rat	LD50	intravenous	236mg/kg (236mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA	Chemotherapy Vol. 32(Suppl,
rat	LD50	oral	> 5gm/kg (5000mg/kg)	?	Chemotherapy Vol. 32(Suppl,
rat	LD50	subcutaneous	> 2gm/kg (2000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Chemotherapy Vol. 32(Suppl,

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Enoxacin cas no:74011-58-8

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