74050-97-8|Haloperidol decanoateProducts Supply - Chemical intermediates Network

Haloperidol decanoate cas no:74050-97-8

Synonyms: Haldoldecanoate;Halomonth;KD 136;KD 16;Neoperidole;R13762;

Identification

NameHaloperidol decanoate
CAS74050-97-8
SynonymsHaldoldecanoate;Halomonth;KD 136;KD 16;Neoperidole;R13762;
EINECS(EC#)277-679-7
Molecular FormulaC₃₁H₄₁ClFNO₃
Molecular Weight530.11

Chemical Properties

refractive index1.554

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Safety

Poison by intraperitoneal route. Moderately toxic by ingestion, subcutaneous, and intramuscular routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects: arrhythmias, EKG changes, heart rate changes. When heated to decomposition it emits toxic fumes of F−, Cl−, and NOx.
RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intramuscular	> 1gm/kg (1000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
mouse	LD50	intramuscular	> 3500mg/kg (3500mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
mouse	LD50	intraperitoneal	288mg/kg (288mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
mouse	LD50	oral	739mg/kg (739mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
mouse	LD50	subcutaneous	1990mg/kg (1990mg/kg)	SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
rat	LD50	intramuscular	> 1525mg/kg (1525mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
rat	LD50	intraperitoneal	328mg/kg (328mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
rat	LD50	oral	1717mg/kg (1717mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
rat	LD50	subcutaneous	780mg/kg (780mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6731, 1985.
women	TDLo	intravenous	11600ug/kg/4D (11.6mg/kg)	CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION) CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE CARDIAC: CHANGE IN RATE	Annals of Internal Medicine. Vol. 119, Pg. 391, 1993.

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Haloperidol decanoate cas no:74050-97-8

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