742-20-1|2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxideProducts Supply

2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide cas no:742-20-1

Synonyms: 6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide;6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-7-sulfamyl-2H-1,2,4-benzothiadiazine1,1-dioxide;6-Chloro-3-cyclopentylmethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide; Benesal; Ciba 8341-Su; Cyclomethiazide; Cyclometiazid;Cyclopenthiazide; Cyclopentiazid; NSC 107679; Navidreks; Navidrex; Navidrix;Salimed; Salimid; Salurilo-C; Su 8341; Tsiklometiazid; Ultra-Minzil

Identification

Name2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide
CAS742-20-1
Synonyms6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide;6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-7-sulfamyl-2H-1,2,4-benzothiadiazine1,1-dioxide;6-Chloro-3-cyclopentylmethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine1,1-dioxide; Benesal; Ciba 8341-Su; Cyclomethiazide; Cyclometiazid;Cyclopenthiazide; Cyclopentiazid; NSC 107679; Navidreks; Navidrex; Navidrix;Salimed; Salimid; Salurilo-C; Su 8341; Tsiklometiazid; Ultra-Minzil
EINECS(EC#)212-012-5
Molecular FormulaC13H18 Cl N3 O4 S2
Molecular Weight379.91

Chemical Properties

Appearancecrystals
refractive index1.6

Safety Data

Safety

Poison by intravenous route. An antihypertensive agent. When heated to decomposition it emits very toxic fumes of SO_x, NO_x, and Cl⁻.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intravenous	232mg/kg (232mg/kg)	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 131, Pg. 325, 1961.
mouse	LD50	oral	> 1gm/kg (1000mg/kg)	Drugs in Japan Vol. 6, Pg. 314, 1982.
rat	LD50	intravenous	142mg/kg (142mg/kg)	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 131, Pg. 325, 1961.
rat	LD50	oral	1gm/kg (1000mg/kg)	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 21, Pg. 775, 1979.

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XinFu chemical & biological technology Co., Ltd.: Tel:+86-010-67226988; Address: Tranport Office, 9 Flour, DaHongMen Business Park, FengTai District, No. 15, BeiJing, China

2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide cas no:742-20-1

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