Osmium cas no:7440-04-2

NameOsmium
CAS7440-04-2
SynonymsNSC 607770;NSC 607771; NSC 607772
EINECS(EC#)231-114-0
Molecular FormulaOs
Molecular Weight190.20

Hazardclass4.1

Hazard Highly toxic; irritant to skin.
Risk 11-37/38-41-36/38
Safety

Poison by intravenous route. An irritant to eyes and mucous membranes. The principal effects of exposure are ocular disturbances and an asthmatic condition caused by inhalation. Furthermore, it causes dermatitis and ulceration of the skin upon contact. When osmium is heated, it gives off a pungent, poisonous fume of osmium tetroxide. One case of osmium poisoning reported in the literature resulted from the inhalation of osmium, which gave rise to a capillary bronchitis and dermatitis. The tetroxide vapor has a pronounced and nauseating odor that should be taken as a warning of a possibly toxic concentration in the atmosphere, and personnel should immediately move to an area of fresh air. The metal itself is not highly toxic. Flammable in the form of dust when exposed to heat or flame. Slight explosion hazard in the form of dust when exposed to heat or flame. Violent reaction or ignition with chlorine trichloride or oxygen difluoride. Ignites when heated to 100°C with fluorine. Incandescent reaction in phosphorus vapor. When heated to decomposition it emits toxic fumes of OsO₄. See also OSMIUM TETROXIDE.
Hazard Codes: F,Xi
Risk Statements: 11-37/38-41-36/38 
R11: Highly flammable. 
R36/38: Irritating to eyes and skin. 
R37/38: Irritating to respiratory system and skin. 
R41: Risk of serious damage to the eyes.
Safety Statements: 16-26-36/37/39 
S16: Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	17mg/kg (17mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: NAUSEA OR VOMITING	Scottish Medical and Surgical Journal. Vol. 26, Pg. 131, 1826.