745-65-3|Prostaglandin E1Products Supply - Chemical intermediates Network

Prostaglandin E1 cas no:745-65-3

Synonyms: ALPROSTADIL; Prostaglandin E1 or AIPROSTADIL; Alprostadil (prostandin E1)

Identification

NameProstaglandin E1
CAS745-65-3
SynonymsALPROSTADIL; Prostaglandin E1 or AIPROSTADIL; Alprostadil (prostandin E1)
EINECS(EC#)212-017-2
Molecular FormulaC20H34O5
Molecular Weight354.48

Chemical Properties

Appearancewhite to off-white crystalline powder
alpha-64 o (C=1.0, C2H5OH)
storage temp?20°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Hazard Xn:Harmful
Risk R22
Safety

Safety Information of Alprostadil (CAS NO.745-65-3):
Hazard Codes: Xn Harmful ,Xi Irritant
Risk Statements: 22-36/37/38
22:? Harmful if swallowed?
36:? Irritating to the eyes?
37:? Irritating to the respiratory system?
38:? Irritating to the skin?
Safety Statements: 36-26
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing

HS Code 29375000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	19800ug/kg (19.8mg/kg)	?	Drugs in Japan Vol. 6, Pg. 47, 1982.
mouse	LD50	intravenous	21mg/kg (21mg/kg)	?	Drugs in Japan Vol. 6, Pg. 47, 1982.
mouse	LD50	oral	186mg/kg (186mg/kg)	?	Drugs in Japan Vol. 6, Pg. 47, 1982.
mouse	LD50	subcutaneous	26400ug/kg (26.4mg/kg)	?	Drugs in Japan Vol. 6, Pg. 47, 1982.
rat	LD50	intraarterial	21mg/kg (21mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 25, Pg. 499, 1983.
rat	LD50	intraperitoneal	24900ug/kg (24.9mg/kg)	?	Drugs in Japan Vol. 6, Pg. 47, 1982.
rat	LD50	intravenous	19200ug/kg (19.2mg/kg)	?	Drugs in Japan Vol. 6, Pg. 47, 1982.
rat	LD50	oral	228mg/kg (228mg/kg)	?	Drugs in Japan Vol. 6, Pg. 47, 1982.
rat	LD50	subcutaneous	18600ug/kg (18.6mg/kg)	?	Drugs in Japan Vol. 6, Pg. 47, 1982.

supplier list

Andard-Mount Company Limited: Tel:020-8991-5150; Address: 20 HANOVER SQUARE,LONDON,W1S 1JY

Hangzhou Rongda Pharm & Chem Co, Ltd.: Tel:0571-28889928; Address: Xinqiao Development Zone, Yuhang, Hangzhou, China

Aliapharm: Tel:+49 69 971412-0; Address: AliaPharm GmbH Frankfurt Niedenau 49 60325 Frankfurt / Main

N-Techem International Co.Ltd.: Tel:; Address: Room 803, B Building, LiYuanShangDu, 39#, 158 Lane, HuanCheng XiLu, Ningbo, Zhejiang, China

Shanghai Techwell Biopharmaceutical Co., Ltd: Tel:; Address: 4258 Jindu Road Shanghai P. R. China

HANGZHOU THINK CHEMICAL CO., LTD.: Tel:; Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU CHINA

AZAD FINE CHEMICALS Limited Liability Company: Tel:; Address:

Bulk Pharmaceuticals Inc.: Tel:+1 416 321-3551; Address: 445 Milner Ave., Unit #1 Scarborough, ON Canada

Unispec Chemicals Co.ltd: Tel:; Address: B2302 Technology Building, No.5 New Model Road, Nanjing, China P.C

Aceto Corporation: Tel:+1-(516)-627-6000; Address: One Hallow Lane, Lake Success, New York 11042-1215,

CarboMer, Inc.: Tel:+1-(858)-552 0992; Address: P. O. Box 261026, San Diego, California 92196,

Attix Corporation: Tel:+1-(416)-345-0071; Address: 120 Carlton Street, Suite 408, Toronto, Ontario M5A 4K2,

Inter-Chemical Ltd.: Tel:+86-(755)-82187211, 82192202; Address: B-1108/1109, Tian An International Bldg., RenMin Nan Road, ShenZhen 518005,

Shanghai BenRo Chemical Co., Ltd.: Tel:+86-(21)-52178644; Address: Rm510, No. 689, Shuicheng Road, Shanghai 200336,

Olly Chem Co., Ltd.: Tel:+86-(24)-6225 9849, 6225 9848; Address: Jiancai Building,Suite 501, Floor 5,44 Hepingbei Street, Shenyang 110002,

Prostaglandin E1 cas no:745-65-3

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