1,3,8-Triazaspiro[4.5]decan-4-one,8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl- cas no:749-02-0

Name1,3,8-Triazaspiro[4.5]decan-4-one,8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-
CAS749-02-0
Synonyms1,3,8-Triazaspiro[4.5]decan-4-one,8-[3-(p-fluorobenzoyl)propyl]-1-phenyl- (7CI,8CI);8-[3-(4-Fluorobenzoyl)propyl]-4-oxo-1-phenyl-1,3,8-triazaspiro[4,5]decane;8-[3-(p-Fluorobenzoyl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; NSC170983; R 5147; Spiperone; Spiroperidol; Spiroperidone; Spiropitan
EINECS(EC#)212-024-0
Molecular FormulaC23H26 F N3 O2
Molecular Weight395.52

storage tempStore at RT

Hazard Xn
Risk 22-63
Safety

Poison by intravenous and intramuscular routes. Moderately toxic by ingestion. An experimental teratogen. When heated to decomposition it emits very toxic fumes of F⁻ and NO_x. See also FLUORIDES.
Hazard Codes: Xn
Risk Statements: 22-63 
R22: Harmful if swallowed. 
R63: Possible risk of harm to the unborn child.
Safety Statements: 36/37 
S36/37: Wear suitable protective clothing and gloves.
WGK Germany: 3
RTECS: XX8925000

1.		ivn-rat LD50:14 mg/kg		27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,193.
2.		ims-rat LD50:168 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),380.
3.		orl-mus LD50:600 mg/kg		CHTPBA    Chimica Therapeutica. 7 (1972),493.
4.		ivn-mus LD50:25,500 µg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),380.
5.		ims-mus LD50:125 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),380.