75-05-8|AcetonitrileProducts Supply - Chemical intermediates Network

Acetonitrile cas no:75-05-8

Synonyms: AN; Methyl cyanide; acetonitrile for uv-spectroscopy; acetonitrile B&J brand 4 L; acetonitrile absolute over molecular sieve (H2O <0.001%); Acetonitrile solution; ACETONITRILE GRADIENT; phosphoramidite diluent for pharmacia; cyanomethane

Identification

NameAcetonitrile
CAS75-05-8
SynonymsAN; Methyl cyanide; acetonitrile for uv-spectroscopy; acetonitrile B&J brand 4 L; acetonitrile absolute over molecular sieve (H2O <0.001%); Acetonitrile solution; ACETONITRILE GRADIENT; phosphoramidite diluent for pharmacia; cyanomethane
EINECS(EC#)200-835-2
Molecular FormulaC2H3N
Molecular Weight41.05

Chemical Properties

AppearanceClear liquid
refractive index1.343-1.345
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass3

Safety Data

Hazard F:Flammable
Risk R11;R20/21/22;R36
Safety

Hazard Codes:?F,Xi,Xn,T
Risk Statements: 11-20/21/22-10-36/37/38-23/24/25-41?
R10: Flammable.
R11: Highly flammable.?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.?
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.?
R41: Risk of serious damage to the eyes.
Safety Statements: 16-45-36/37/39-27-26?
S16: Keep away from sources of ignition.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S27: Take off immediately all contaminated clothing.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

HS Code 29269095

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LC50	inhalation	18gm/m3 (18000mg/m3)	?	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 16, 1982.
cat	LD50	oral	200mg/kg (200mg/kg)	?	Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. Vol. 19, Pg. 225, 1969.
child	TDLo	oral	800mg/kg (800mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	American Journal of Emergency Medicine. Vol. 9, Pg. 268, 1991.
dog	LCLo	inhalation	16000ppm/4H (16000ppm)	?	Journal of Occupational Medicine. Vol. 1, Pg. 634, 1959.
frog	LDLo	subcutaneous	9100mg/kg (9100mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 5, Pg. 161, 1899.
guinea pig	LC50	inhalation	5655ppm/4H (5655ppm)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BLOOD: HEMORRHAGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Journal of Occupational Medicine. Vol. 1, Pg. 634, 1959.
guinea pig	LD50	oral	177mg/kg (177mg/kg)	?	Journal of Occupational Medicine. Vol. 1, Pg. 634, 1959.
human	TCLo	inhalation	160ppm/4H (160ppm)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 65, 1969.
mammal (species unspecified)	LD50	oral	1670mg/kg (1670mg/kg)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
man	TDLo	oral	64mg/kg (64mg/kg)	BEHAVIORAL: EXCITEMENT	Journal of Toxicology, Clinical Toxicology. Vol. 29, Pg. 447, 1991.
man	TDLo	oral	571mg/kg (571mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING	Acta Pharmacologica et Toxicologica, Supplementun. Vol. 41, Pg. 340, 1977.
mouse	LC50	inhalation	2693ppm/1H (2693ppm)	LIVER: OTHER CHANGES	Clinical Toxicology. Vol. 18, Pg. 991, 1981.
mouse	LD50	intraperitoneal	175mg/kg (175mg/kg)	SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA	Toxicology and Applied Pharmacology. Vol. 59, Pg. 589, 1981.
mouse	LD50	intravenous	612mg/kg (612mg/kg)	?	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 16, 1982.
mouse	LD50	oral	269mg/kg (269mg/kg)	?	Archives of Toxicology. Vol. 55, Pg. 47, 1984.
mouse	LD50	subcutaneous	4480mg/kg (4480mg/kg)	?	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 16, 1982.
rabbit	LC50	inhalation	2828ppm/4H (2828ppm)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BLOOD: HEMORRHAGE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Journal of Occupational Medicine. Vol. 1, Pg. 634, 1959.
rabbit	LD50	oral	50mg/kg (50mg/kg)	?	Zentralblatt fuer Arbeitsmedizin und Arbeitsschutz. Vol. 19, Pg. 225, 1969.
rabbit	LD50	skin	> 2gm/kg (2000mg/kg)	?	International Journal of Toxicology. Vol. 19, Pg. 363, 2000.
rabbit	LDLo	subcutaneous	105mg/kg (105mg/kg)	?	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 36, Pg. 455, 1929.
rat	LC50	inhalation	7551ppm/8H (7551ppm)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: HEMORRHAGE	Journal of Occupational Medicine. Vol. 1, Pg. 634, 1959.
rat	LD50	intraperitoneal	850mg/kg (850mg/kg)	?	Journal of Occupational Medicine. Vol. 1, Pg. 634, 1959.
rat	LD50	intravenous	1680mg/kg (1680mg/kg)	?	Journal of Occupational Medicine. Vol. 1, Pg. 634, 1959.
rat	LD50	oral	2460mg/kg (2460mg/kg)	?	Union Carbide Data Sheet. Vol. 3/18/1965,
rat	LD50	parenteral	1100mg/kg (1100mg/kg)	?	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 16, 1982.
rat	LD50	subcutaneous	3500mg/kg (3500mg/kg)	?	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 16, 1982.
women	TDLo	oral	500mg/kg (500mg/kg)	BEHAVIORAL: COMA CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Postgraduate Medical Journal. Vol. 73, Pg. 299, 1997. ?

supplier list

AerChem and Xena International LLC: Tel:812-334-9996; Address: P.O. Box 177

Shanghai Haodeng Chemical Co.,Ltd.: Tel:; Address: No.587,Shatian Mansion, Changshou Road,Shanghai

Griffin International Inc: Tel:1-718-7943113; Address: 80 Westchester Square, 2nd Floor, Bronx, New York 10461 USA

ZHEJIANG CHEMIALS IM & EXP CORP.: Tel:86-571-87048079; Address: No.37,Qingchun Road,Hangzhou,China

Seidler Chemical Co., Inc.: Tel:+1-973-4651122; Address: 537 Raymond Boulevard Newark, NJ 07105

Shanghai Mingdou Chemical Co.,Ltd: Tel:86-21-52912919; Address: Floor 12th, Zhenyuan Building ,No 2052.North Zhongshan Road, Shanghai,China

Hangzhou Greenda Chemical Co.Ltd.: Tel:; Address: 2#B102,4028 Nanhuan Road,Binjiang District, Hangzhou,China

Zhejiang Sunrise Chemicals Co., Ltd.: Tel:+86-21-62144089; Address: 22nd Fl.East Sea Sunshine Building No.455 Zhongshan East Rd. Ningbo Zhejiang China

Cambridge Isotope: Tel:+1-978-749-8000; Address: Cambridge Isotope Laboratories 50 Frontage Road Andover, MA 01810-5413

Hangzhou Kinsey Bio-tech Co., Ltd.: Tel:; Address: 1207, Taihe International Mansion, No.1 Building 168 Chaohui Road, Hangzhou, China

Jiangxi Chibang Pharmaceutical Co.,Ltd: Tel:; Address: Hejiaping Baqiu Town Xiajiang County Jiangxi

Fine Chem Trading LTD: Tel:+44-079-7062-7591; Address: PO Box 292, Greenford, UB6 9ZL, England

Shanghai Longschem Co.,Ltd: Tel:; Address: Shanghai Jincheng Road 338 6# 1002 Room

Shanghai Experiment Reagent Co.,LTD.: Tel:0086-21-56558317 56553837; Address: 10-603, No.555 Luding Road (No.1000 North Zhongshan Road),Shanghai

China Chem Source (HK) Co.,Ltd: Tel:+86-411-82808830 82649412 82649140 82647982 82659338; Address: Room 1818, The Bank of East Asia Mansion , Dalian , 116001, China.

Acetonitrile cas no:75-05-8

Directory

supplier list