75-09-2|DichloromethaneProducts Supply - Chemical intermediates Network

Dichloromethane cas no:75-09-2

Synonyms: Methylene chloride; Methane dichloride; Methylene dichloride; narkotil; Plastisolve; R 30; Refrigerant 30; solaesthin; solmethine;Freon 30; Methylene bichloride; Methane,dichloro; Dichloromethane;

Identification

NameDichloromethane
CAS75-09-2
SynonymsMethylene chloride; Methane dichloride; Methylene dichloride; narkotil; Plastisolve; R 30; Refrigerant 30; solaesthin; solmethine;Freon 30; Methylene bichloride; Methane,dichloro; Dichloromethane;
EINECS(EC#)200-838-9
Molecular FormulaCH2Cl2
Molecular Weight84.93260

Chemical Properties

AppearanceA colorless liquid with a sweet, penetrating, ether-like odor
refractive index1.4242
storage tempStore at RT.

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1

Safety Data

Hazard Xn:Harmful
Risk R40
Safety Hazard Codes of Dichloromethane (CAS NO.75-09-2):?Xn,T,F
Risk Statements: 40-39-23/24/25-11
R40:Limited evidence of a carcinogenic effect.
R39:Danger of very serious irreversible effects.
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.
R11:Highly flammable.
Safety Statements: 23-24/25-36/37-45-16-7
S23:Do not breathe vapour.
S24/25:Avoid contact with skin and eyes.
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S16:Keep away from sources of ignition.
S7:Keep container tightly closed.
RIDADR: UN 1593 6.1/PG 3
WGK Germany: 2
RTECS: PA8050000
F: 3-10
Hazard Note: Harmful
HazardClass: 6.1
PackingGroup: III
HS Code 2903120001

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LCLo	inhalation	43400mg/m^3/4. (43400mg/m³)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: ATAXIA	Archiv fuer Hygiene und Bakteriologie. Vol. 116, Pg. 131, 1936.
dog	LCLo	inhalation	14108ppm/7H (14108ppm)	SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: DYSPNEA	National Institutes of Health, Bulletin. Vol. 191, Pg. 1, 1949.
dog	LD50	intraperitoneal	1274mg/kg (1274mg/kg)		Toxicology and Applied Pharmacology. Vol. 10, Pg. 119, 1967.
dog	LDLo	intravenous	200mg/kg (200mg/kg)		Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
dog	LDLo	oral	3gm/kg (3000mg/kg)		Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
guinea pig	LCLo	inhalation	5000ppm/2H (5000ppm)		Fluorine Chemistry Reviews. Vol. 1, Pg. 197, 1967.
human	LDLo	oral	357mg/kg (357mg/kg)	PERIPHERAL NERVE AND SENSATION: PARESTHESIS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 390, 1969.
human	TCLo	inhalation	500ppm/1Y-I (500ppm)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) CARDIAC: CHANGE IN RATE	Abstracts on Hygiene. Vol. 43, Pg. 1123, 1968.
human	TCLo	inhalation	500ppm/8H (500ppm)	BEHAVIORAL: EUPHORIA	Science. Vol. 176, Pg. 295, 1972.
man	TDLo	oral	1429uL/kg (1.429mL/kg)	KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: NORMOCYTIC ANEMIA	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 36, Pg. 575, 1994.
mouse	LC50	inhalation	14400ppm/7H (14400ppm)		National Institutes of Health, Bulletin. Vol. 191, Pg. 1, 1949.
mouse	LD50	intraperitoneal	437mg/kg (437mg/kg)		Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 18, Pg. 109, 1960.
mouse	LD50	oral	873mg/kg (873mg/kg)		EHP, Environmental Health Perspectives. Vol. 106(Suppl,
mouse	LD50	subcutaneous	6460mg/kg (6460mg/kg)		Toxicology and Applied Pharmacology. Vol. 4, Pg. 354, 1962.
mouse	LD50	unreported	4770mg/kg (4770mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Eisei Kagaku. Hygienic Chemistry. Vol. 28, Pg. P31, 1982.
rabbit	LCLo	inhalation	10000ppm/7H (10000ppm)		Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 8, 1944.
rabbit	LD50	unreported	1225mg/kg (1225mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(6), Pg. 78, 1988.
rabbit	LDLo	oral	1900mg/kg (1900mg/kg)		"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 94, 1955.
rabbit	LDLo	subcutaneous	2700mg/kg (2700mg/kg)		Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
rat	LC50	inhalation	52gm/m³ (52000mg/m³)		Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 15, Pg. 64, 1979.
rat	LD50	intraperitoneal	916mg/kg (916mg/kg)		Environmental Research. Vol. 40, Pg. 411, 1986.
rat	LD50	oral	1600mg/kg (1600mg/kg)	BEHAVIORAL: ATAXIA	FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 94, 1970.
rat	LD50	unreported	5350mg/kg (5350mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(6), Pg. 78, 1988.
rat	LDLo	intratracheal	350mg/kg (350mg/kg)	LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	National Technical Information Service. Vol. OTS0520615,

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Dichloromethane cas no:75-09-2

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