75-21-8|Ethylene oxideProducts Supply - Chemical intermediates Network

Ethylene oxide cas no:75-21-8

Synonyms: Ethyleneoxide (8CI);Ethyleneoxy (6CI);1,2-Epoxyethane;Dihydrooxirene;Dimethylene oxide;ETO;Epoxyethane;Ethene oxide;Oxacyclopropane;Oxane;Oxidoethane;Oxirene, dihydro-;Oxyfume;Oxyfume 12;Oxyfume 2002;T-Gas;

Identification

NameEthylene oxide
CAS75-21-8
SynonymsEthyleneoxide (8CI);Ethyleneoxy (6CI);1,2-Epoxyethane;Dihydrooxirene;Dimethylene oxide;ETO;Epoxyethane;Ethene oxide;Oxacyclopropane;Oxane;Oxidoethane;Oxirene, dihydro-;Oxyfume;Oxyfume 12;Oxyfume 2002;T-Gas;
EINECS(EC#)200-849-9
Molecular FormulaC2H4O
Molecular Weight44.053

Chemical Properties

AppearanceCOLOURLESS COMPRESSED LIQUEFIED GAS.
refractive indexn20/D 1.3597(lit.)
storage tempRefrigerator

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass2.3

Safety Data

Hazard Irritant to eyes and skin. TLV: 1 ppm; suspected human carcinogen. Highly flammable, dangerous fire and explosion risk, flammable limits in air 3–100%.
Risk R45
Safety

Hazard Codes?of Ethylene oxide (CAS NO.75-21-8): F+,T,F
Risk Statements: 45-46-12-23-36/37/38-39/23/24/25-23/24/25-11
45: May cause cancer?
46: May cause heritable genetic damage???
12: Extremely Flammable?
23: Toxic by inhalation?
36/37/38: Irritating to eyes, respiratory system and skin?
39/23/24/25:?Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed?
23/24/25:?Toxic by inhalation, in contact with skin and if swallowed?
11: Highly Flammable
Safety Statements: 53-45-36/37-16-24/25-23
53: Avoid exposure - obtain special instruction before use?
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)?
36/37:?Wear suitable protective clothing and gloves?
16: Keep away from sources of ignition - No smoking?
24/25: Avoid contact with skin and eyes?
23: Toxic by inhalation
RIDADR: UN 2037 2.3
WGK Germany: 2
F: 4.5-31: Do not heat over 50 °C.Do not puncture.
HazardClass: 2.3

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	subcutaneous	100mg/kg (100mg/kg)	?	"Beitrage zur Toxikologie des Athylenoxyds und der Glykole, Dissertation," Hofbauer, A., Pharmakologischen Institut der Universitat Wurzburg, Fed. Rep. Ger., 1933Vol. -, Pg. -, 1933.
dog	LC50	inhalation	960ppm/4H (960ppm)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	AMA Archives of Industrial Health. Vol. 13, Pg. 237, 1956.
dog	LD50	intravenous	330mg/kg (330mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Journal of Thoracic and Cardiovascular Surgery. Vol. 61, Pg. 309, 1971.
guinea pig	LC50	inhalation	1500mg/m3/4H (1500mg/m3)	?	"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 67, 1982.
guinea pig	LD50	oral	270mg/kg (270mg/kg)	?	Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
human	TCLo	inhalation	12500ppm/10S (12500ppm)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION	Journal of Hygiene. Vol. 32, Pg. 409, 1932.
mouse	LC50	inhalation	836ppm/4H (836ppm)	?	National Technical Information Service. Vol. PB214-270,
mouse	LD50	intraperitoneal	175mg/kg (175mg/kg)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(1), Pg. 23, 1983.
mouse	LD50	intravenous	290mg/kg (290mg/kg)	?	Acta Pharmacologica et Toxicologica. Vol. 43, Pg. 69, 1978.
rabbit	LDLo	intravenous	175mg/kg (175mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: REGIDITY	Journal of Hygiene. Vol. 32, Pg. 409, 1932.
rat	LC50	inhalation	800ppm/4H (800ppm)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES LIVER: OTHER CHANGES	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 258, 1969.
rat	LD50	oral	72mg/kg (72mg/kg)	?	Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 17, 1978.
rat	LD50	subcutaneous	187mg/kg (187mg/kg)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(1), Pg. 23, 1983.
rat	LDLo	unreported	200mg/kg (200mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LIVER: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 258, 1969.
women	TCLo	inhalation	500ppm/2M (500ppm)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Drug Intelligence and Clinical Pharmacy. Vol. 15, Pg. 384, 1981.

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Ethylene oxide cas no:75-21-8

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