Tetramethylammonium hydroxide cas no:75-59-2
Synonyms: N,N,N-TRIMETHYLMETHANAMINIUM HYDROXIDE; TMAH; hydroxydedetetramethylammonium; megapositcd14; Methanaminium,N,N,N-trimethyl-,hydroxide; n,n,n-trimethyl-methanaminiuhydroxide; nmd3; 104422-11-9; 105468-35-7; 123626-97-1; 129653-91-4; 129654-61-1; 143549-79-5; 154636-59-6; 195460-17-4; 78017-87-5; 93615-68-0
NameTetramethylammonium hydroxide
CAS75-59-2
SynonymsN,N,N-TRIMETHYLMETHANAMINIUM HYDROXIDE; TMAH; hydroxydedetetramethylammonium; megapositcd14; Methanaminium,N,N,N-trimethyl-,hydroxide; n,n,n-trimethyl-methanaminiuhydroxide; nmd3; 104422-11-9; 105468-35-7; 123626-97-1; 129653-91-4; 129654-61-1; 143549-79-5; 154636-59-6; 195460-17-4; 78017-87-5; 93615-68-0
EINECS(EC#)200-882-9
Molecular FormulaC4H13NO
Molecular Weight91.15
Appearancecolourless to yellow liquid
refractive index1.3806
storage temp2-8°C
Sensitive Air Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3
Hazard C:Corrosive
Risk R20/21/22;R34
Safety
Poison by subcutaneous route. A powerful caustic. A corrosive irritant to skin, eyes, and mucous membranes. When heated to decomposition it emits toxic fumes of NOx and NH3.
Hazard Codes: C,T,F
Risk Statements: 24/25-34-20/21/22-39/23/24/25-23/24/25-10-21/22-25-21-11-67-36?
R24:Toxic in contact with skin.?
R25 :Toxic if swallowed.?
R34:Causes burns.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R10:Flammable.?
R21/22:Harmful in contact with skin and if swallowed.?
R11:Highly flammable.?
R25 :Toxic if swallowed.?
R21:Harmful in contact with skin.?
R67:Vapours may cause drowsiness and dizziness.?
R36:Irritating to eyes.
Safety Statements: 45-36/37/39-26-16-36/37?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S16:Keep away from sources of ignition.?
S36/37:Wear suitable protective clothing and gloves.
RIDADR: UN 3286 3/PG 2
WGK Germany: 1
F: 4.4-10-34
HazardClass: 3
PackingGroup: II
HS Code 29239000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| frog |
LDLo |
parenteral |
5mg/kg (5mg/kg) |
VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION |
"Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 688, 1948. |
| frog |
LDLo |
unreported |
1515ug/kg (1.515mg/kg) |
? |
"Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 681, 1948. |
| guinea pig |
LD50 |
skin |
25mg/kg (25mg/kg) |
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" |
National Technical Information Service. Vol. OTS0570994, |
| mouse |
LDLo |
subcutaneous |
19mg/kg (19mg/kg) |
? |
Journal of Pharmacology and Experimental Therapeutics. Vol. 28, Pg. 367, 1926. |
| rabbit |
LDLo |
intravenous |
1mg/kg (1mg/kg) |
? |
"Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 688, 1948. |
