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2-Methyl-2-butanol cas no:75-85-4

Synonyms: tert-Amyl alcohol; 1,1-Dimethyl-1-propanol; tert-Pentyl alcohol; T-amyl alcohol; Sultamicillin; TAA

Identification
Name2-Methyl-2-butanol
CAS75-85-4
Synonymstert-Amyl alcohol; 1,1-Dimethyl-1-propanol; tert-Pentyl alcohol; T-amyl alcohol; Sultamicillin; TAA
EINECS(EC#)200-908-9
Molecular FormulaC5H12O
Molecular Weight88.15
Chemical Properties
AppearanceClear, colorless liquid
refractive index1.404-1.406
storage tempFlammables area
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3
Safety Data

Hazard F:Flammable
Risk R11;R20;R37/38
Safety

Hazard Codes of?2-Methyl-2-butanol (CAS NO.75-85-4):?F,Xn
Risk Statements: 11-20-37/38?
R11: Highly flammable.?
R20: Harmful by inhalation.?
R37/38: Irritating to respiratory system and skin.
Safety Statements: 46?
S46: If swallowed, seek medical advice immediately and show this container or label.
RIDADR: UN 1105 3/PG 2
WGK Germany: 1
RTECS: SC0175000
HazardClass: 3
PackingGroup: II
HS Code: 29051500


HS Code 29051500

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo parenteral 4gm/kg (4000mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 296, 1935.
man LDLo unreported 441mg/kg (441mg/kg) ? "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse LD50 intravenous 610mg/kg (610mg/kg) ? Archives Internationales de Pharmacodynamie et de Therapie. Vol. 135, Pg. 330, 1962.
mouse LD50 subcutaneous 2100mg/kg (2100mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 161, 1955.
mouse LDLo intraperitoneal 2gm/kg (2000mg/kg) ? Skandinavisches Archiv fuer Physiologie. Vol. 79, Pg. 258, 1938.
mouse LDLo oral 2500mg/kg (2500mg/kg) ? "Narkoseversuche mit Hoheren Alkoholen und Stickstoffderivaten, Dissertation," Leube, F., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1931Vol. -, Pg. -, 1931.
rabbit LD50 oral 2028mg/kg (2028mg/kg) SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE

CARDIAC: PULSE RATE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.
rat LCLo inhalation 5700ppm/6H (5700ppm) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) National Technical Information Service. Vol. OTS0536478,
rat LD50 oral 1gm/kg (1000mg/kg) BEHAVIORAL: ATAXIA Science. Vol. 116, Pg. 663, 1952.
rat LDLo intraperitoneal 1530mg/kg (1530mg/kg) ? Journal of Industrial Hygiene and Toxicology. Vol. 27, Pg. 1, 1945.
rat LDLo rectal 1400mg/kg (1400mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 49, Pg. 36, 1933.
rat LDLo subcutaneous 1400mg/kg (1400mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 49, Pg. 36, 1933.

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