75-89-8|2,2,2-TrifluoroethanolProducts Supply - Chemical intermediates Network

2,2,2-Trifluoroethanol cas no:75-89-8

Synonyms: TFE; Trifluoroethanol; Trifluroroethyl alchohol

Identification

Name2,2,2-Trifluoroethanol
CAS75-89-8
SynonymsTFE; Trifluoroethanol; Trifluroroethyl alchohol
EINECS(EC#)200-913-6
Molecular FormulaC2H3F3O
Molecular Weight100.04

Chemical Properties

AppearanceColorless liquid
refractive index1.2907
storage tempStore at RT.

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass3

Safety Data

Hazard Xn:Harmful
Risk R10;R20/21/22;R38;R41;R62
Safety

Poison by ingestion, intravenous, and intraperitoneal routes. Moderately toxic by inhalation and skin contact. Experimental reproductive effects. A severe skin and eye irritant. When heated to decomposition it emits toxic fumes of F^?.
Hazard Codes:?Xn, T, F
Hazard Note: Flammable/Toxic
The Risk Statements information of?2,2,2-Trifluoroethanol (CAS NO.75-89-8):
10:? Flammable?
41:? Risk of serious damage to eyes?
62:? Possible risk of impaired fertility?
20/21/22:? Harmful by inhalation, in contact with skin and if swallowed?
37/38:? Irritating to respiratory system and skin?
36/37/38:? Irritating to eyes, respiratory system and skin?
The Safety Statements information of??2,2,2-Trifluoroethanol (CAS NO.75-89-8):
16:? Keep away from sources of ignition - No smoking?
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing?
39:? Wear eye/face protection?
45:? In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)?
36/37/39:? Wear suitable protective clothing, gloves and eye/face protection??
RIDADR: UN 1986 3/PG 3
WGK Germany: 1
RTECS: KM5250000
Hazard Note: Flammable/Toxic
HazardClass: 3
PackingGroup: III
HS Code: 29055910

HS Code 29055910

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	400mg/kg (400mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Toxicology and Applied Pharmacology. Vol. 15, Pg. 83, 1969.
mouse	LC50	inhalation	2900mg/m³ (2900mg/m³)	BRAIN AND COVERINGS: "CHANGES IN CIRCULATION (HEMORRHAGE, THROMBOSIS, ETC.)" BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 13(10), Pg. 29, 1969.
mouse	LD50	intraperitoneal	158mg/kg (158mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Annales Medicinae Experimentalis et Biologiae Fenniae. Vol. 46, Pg. 242, 1968.
mouse	LD50	intravenous	250mg/kg (250mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Annales Medicinae Experimentalis et Biologiae Fenniae. Vol. 46, Pg. 242, 1968.
mouse	LD50	oral	366mg/kg (366mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Toxicology and Applied Pharmacology. Vol. 15, Pg. 83, 1969.
rabbit	LD50	skin	390uL/kg (0.39mL/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	National Technical Information Service. Vol. OTS0555986,
rat	LC50	inhalation	470ppm/6H (470ppm)	BEHAVIORAL: TREMOR BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): HAIR: OTHER	National Technical Information Service. Vol. OTS0555986,
rat	LD50	intraperitoneal	210mg/kg (210mg/kg)	?	Toxicology and Applied Pharmacology. Vol. 71, Pg. 84, 1983.
rat	LD50	oral	240mg/kg (240mg/kg)	?	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 607, 1969.
rat	LD50	skin	1680mg/kg (1680mg/kg)	?	"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 607, 1969.

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2,2,2-Trifluoroethanol cas no:75-89-8

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