Penicillin G Benethamine cas no:751-84-8

NamePenicillin G Benethamine
CAS751-84-8
SynonymsN-benzylphenethylammonium 6-phenylacetamidopenicillanate;3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N-benzyl-2-phenylethanamine (1:1)
EINECS(EC#)212-029-8
Molecular FormulaC31H35N3O4S
Molecular Weight545.6923

Safety

Poison by intravenous route. When heated to decomposition it emits toxic fumes of SO_x and NO_x. See also PENICILLIN.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	170mg/kg (170mg/kg)	Behavioral: convulsions or effect on seizure threshold	Antibiotics and Chemotherapy Vol. 5, Pg. 152, 1955.
mouse	LDLo	oral	> 10gm/kg (10000mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 152, 1955.
mouse	LDLo	subcutaneous	> 7gm/kg (7000mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 152, 1955.
rabbit	LD50	intravenous	55mg/kg (55mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 152, 1955.
rat	LD50	intravenous	122mg/kg (122mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 152, 1955.
rat	LD50	subcutaneous	> 6gm/kg (6000mg/kg)		Antibiotics and Chemotherapy Vol. 5, Pg. 152, 1955.