2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-,(4S,4aS,5aS,6S,12aS)- cas no:751-97-3

Name2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-,(4S,4aS,5aS,6S,12aS)-
CAS751-97-3
Synonyms2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-(6CI,8CI); 2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-,[4S-(4a,4aa,5aa,6b,12aa)]-;4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-N-(1-pyrrolidinylmethyl)-2-naphthacenecarboxamide;Abricycline; Bristacin; N-(1-Pyrrolidinylmethyl)tetracycline;N-(Pyrrolidinomethyl)tetracycline; Pyrrolidinylmethyltetracycline; Reverin;Rolitetracycline; SQ 15659; Superciclin; Synotodecin; Syntetrin; Tetraverin;Transcycline; Velacycline
EINECS(EC#)212-031-9
Molecular FormulaC27H33 N3 O8
Molecular Weight527.63

refractive index1.713

Hazard Xn
Risk 22-36/37/38
Safety

Poison by intravenous route. Experimental teratogenic effects. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.
Safety Information of Rolitetracycline (CAS NO.751-97-3):
Hazard Codes: Xn
Risk Statements: 22-36/37/38 
22:  Harmful if swallowed
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
Safety Statements: 26-36
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	93mg/kg (93mg/kg)		Drugs in Japan Vol. 6, Pg. 914, 1982.
mouse	LD50	intraperitoneal	225mg/kg (225mg/kg)		United States Patent Document. Vol. #3846486,
mouse	LD50	intravenous	75mg/kg (75mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 9, Pg. 63, 1959.
mouse	LD50	oral	1320mg/kg (1320mg/kg)		Journal of Pharmacy and Pharmacology. Vol. 16, Pg. 33, 1964.
rabbit	LD50	intravenous	47mg/kg (47mg/kg)		Drugs in Japan Vol. 6, Pg. 914, 1982.