75607-67-9|Fludarabine phosphateProducts Supply - Chemical intermediates Network

Fludarabine phosphate cas no:75607-67-9

Synonyms: Fludarabine phosphate (JAN/USP);Fludarabine 5-monophosphate;9-beta-D-Arabinofuranosyl-2-fluoroadenine 5-(dihydrogen phosphate);Trimeric Sodium Phosphate;[(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid;2-Fluoro-ARA AMP;Fludarabine phosphate [USAN:BAN];Fludarabine monophosphate;9-beta-Arabinofuranosyl-2-fluoroadenine-5-phosphate;Fludura;9H-Purin-6-amine, 2-fluoro-9-(5-O-phosphono-.beta.-D-arabinofuranosyl)-;2-Fluoroadenine arabinoside 5-monophosphate;fludarabine hcl;

Identification

NameFludarabine phosphate
CAS75607-67-9
SynonymsFludarabine phosphate (JAN/USP);Fludarabine 5-monophosphate;9-beta-D-Arabinofuranosyl-2-fluoroadenine 5-(dihydrogen phosphate);Trimeric Sodium Phosphate;[(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid;2-Fluoro-ARA AMP;Fludarabine phosphate [USAN:BAN];Fludarabine monophosphate;9-beta-Arabinofuranosyl-2-fluoroadenine-5-phosphate;Fludura;9H-Purin-6-amine, 2-fluoro-9-(5-O-phosphono-.beta.-D-arabinofuranosyl)-;2-Fluoroadenine arabinoside 5-monophosphate;fludarabine hcl;
Molecular FormulaC₁₀H₁₃FN₅O₇P
Molecular Weight365.21

Chemical Properties

refractive index1.878

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	intravenous	18750mg/kg/5D (18750mg/kg)	BRAIN AND COVERINGS: ENCEPHALITIS SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE	Cancer Treatment Reports. Vol. 70, Pg. 1225, 1986.
man	TDLo	intravenous	11655mg/kg/5D (11655mg/kg)	SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Cancer Treatment Reports. Vol. 70, Pg. 1449, 1986.
man	TDLo	intravenous	17760mg/kg/5D (17760mg/kg)	BRAIN AND COVERINGS: DEMYELINATION BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: COMA	Cancer Treatment Reports. Vol. 70, Pg. 1225, 1986.
mouse	LD50	intravenous	1236mg/kg (1236mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	National Technical Information Service. Vol. PB83-195685,
women	LDLo	intravenous	14245mg/kg/5D (14245mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE BEHAVIORAL: EXCITEMENT SKIN AND APPENDAGES (SKIN): SWEATING: OTHER	Cancer Treatment Reports. Vol. 70, Pg. 1449, 1986.
women	TDLo	intravenous	23125mg/kg/5D (23125mg/kg)	BRAIN AND COVERINGS: ENCEPHALITIS SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Cancer Treatment Reports. Vol. 70, Pg. 1225, 1986

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Fludarabine phosphate cas no:75607-67-9

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