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Benzenemethanol, a-(aminomethyl)- cas no:7568-93-6

Synonyms: Benzylalcohol, a-(aminomethyl)- (6CI,8CI);(RS)-2-Amino-1-phenylethanol;(?à)-1-Phenylethanolamine;(?à)-2-Amino-1-phenylethanol;(?à)-Phenylethanolamine;(?à)-a-Phenylglycinol;(?à)-b-Hydroxyphenethylamine;1-Phenyl-1-hydroxy-2-aminoethane;1-Phenyl-2-aminoethanol;1-Phenylethanolamine;2-Amino-1-phenyl-1-ethanol;2-Amino-1-phenylethanol;2-Hydroxy-2-phenylethylamine;2-Phenyl-2-hydroxyethylamine;Apophedrin;Benzeneethanamine, b-hydroxy-;Bisnorephedrine;DL-b-Hydroxy-b-phenethylamine;NSC 46837;NSC 5021;Phenethanolamine;Phenylethanolamine;dl-Phenylethanolamine;dl-b-Hydroxyphenylethylamine;rac-2-Amino-1-phenylethanol;a-(Aminomethyl)benzenemethanol;a-(Aminomethyl)benzyl alcohol;b-Hydroxy-b-phenylethylamine;b-Hydroxyphenethylamine;b-Hydroxyphenylethylamine;b-Phenethanolamine;b-Phenylethanolamine;1936-63-6;

Identification
NameBenzenemethanol, a-(aminomethyl)-
CAS7568-93-6
SynonymsBenzylalcohol, a-(aminomethyl)- (6CI,8CI);(RS)-2-Amino-1-phenylethanol;(?à)-1-Phenylethanolamine;(?à)-2-Amino-1-phenylethanol;(?à)-Phenylethanolamine;(?à)-a-Phenylglycinol;(?à)-b-Hydroxyphenethylamine;1-Phenyl-1-hydroxy-2-aminoethane;1-Phenyl-2-aminoethanol;1-Phenylethanolamine;2-Amino-1-phenyl-1-ethanol;2-Amino-1-phenylethanol;2-Hydroxy-2-phenylethylamine;2-Phenyl-2-hydroxyethylamine;Apophedrin;Benzeneethanamine, b-hydroxy-;Bisnorephedrine;DL-b-Hydroxy-b-phenethylamine;NSC 46837;NSC 5021;Phenethanolamine;Phenylethanolamine;dl-Phenylethanolamine;dl-b-Hydroxyphenylethylamine;rac-2-Amino-1-phenylethanol;a-(Aminomethyl)benzenemethanol;a-(Aminomethyl)benzyl alcohol;b-Hydroxy-b-phenylethylamine;b-Hydroxyphenethylamine;b-Hydroxyphenylethylamine;b-Phenethanolamine;b-Phenylethanolamine;1936-63-6;
EINECS(EC#)231-469-1
Molecular FormulaC8H11 N O
Molecular Weight137.20
Chemical Properties
Appearancewhite solid
refractive index1.558-1.56
Safety Data

Hazard Xi
Risk R36/37/38
Safety

Poison by intraperitoneal and intravenous routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
 

Hazard Codes: IrritantXi,CorrosiveC
Risk Statements: 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo subcutaneous 1gm/kg (1000mg/kg)   "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 73, 1948.
mouse LD50 intraperitoneal 250mg/kg (250mg/kg)   National Technical Information Service. Vol. AD691-490,
mouse LDLo subcutaneous 686mg/kg (686mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 47, Pg. 96, 1934.
mouse LDLo unreported 1100mg/kg (1100mg/kg) AUTONOMIC NERVOUS SYSTEM: SYMPATHOMIMETIC Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 153, Pg. 161, 1930.
rabbit LDLo intravenous 23mg/kg (23mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 47, Pg. 96, 1934.

Carcinogenicity of 2-Hydroxyphenethylamine (CAS NO.7568-93-6) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. And its toxicological properties have not been fully investigated.You can see actual entry in RTECS for complete information.

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