Benzenemethanol, a-(aminomethyl)- cas no:7568-93-6
Synonyms: Benzylalcohol, a-(aminomethyl)- (6CI,8CI);(RS)-2-Amino-1-phenylethanol;(?à)-1-Phenylethanolamine;(?à)-2-Amino-1-phenylethanol;(?à)-Phenylethanolamine;(?à)-a-Phenylglycinol;(?à)-b-Hydroxyphenethylamine;1-Phenyl-1-hydroxy-2-aminoethane;1-Phenyl-2-aminoethanol;1-Phenylethanolamine;2-Amino-1-phenyl-1-ethanol;2-Amino-1-phenylethanol;2-Hydroxy-2-phenylethylamine;2-Phenyl-2-hydroxyethylamine;Apophedrin;Benzeneethanamine, b-hydroxy-;Bisnorephedrine;DL-b-Hydroxy-b-phenethylamine;NSC 46837;NSC 5021;Phenethanolamine;Phenylethanolamine;dl-Phenylethanolamine;dl-b-Hydroxyphenylethylamine;rac-2-Amino-1-phenylethanol;a-(Aminomethyl)benzenemethanol;a-(Aminomethyl)benzyl alcohol;b-Hydroxy-b-phenylethylamine;b-Hydroxyphenethylamine;b-Hydroxyphenylethylamine;b-Phenethanolamine;b-Phenylethanolamine;1936-63-6;
NameBenzenemethanol, a-(aminomethyl)-
CAS7568-93-6
SynonymsBenzylalcohol, a-(aminomethyl)- (6CI,8CI);(RS)-2-Amino-1-phenylethanol;(?à)-1-Phenylethanolamine;(?à)-2-Amino-1-phenylethanol;(?à)-Phenylethanolamine;(?à)-a-Phenylglycinol;(?à)-b-Hydroxyphenethylamine;1-Phenyl-1-hydroxy-2-aminoethane;1-Phenyl-2-aminoethanol;1-Phenylethanolamine;2-Amino-1-phenyl-1-ethanol;2-Amino-1-phenylethanol;2-Hydroxy-2-phenylethylamine;2-Phenyl-2-hydroxyethylamine;Apophedrin;Benzeneethanamine, b-hydroxy-;Bisnorephedrine;DL-b-Hydroxy-b-phenethylamine;NSC 46837;NSC 5021;Phenethanolamine;Phenylethanolamine;dl-Phenylethanolamine;dl-b-Hydroxyphenylethylamine;rac-2-Amino-1-phenylethanol;a-(Aminomethyl)benzenemethanol;a-(Aminomethyl)benzyl alcohol;b-Hydroxy-b-phenylethylamine;b-Hydroxyphenethylamine;b-Hydroxyphenylethylamine;b-Phenethanolamine;b-Phenylethanolamine;1936-63-6;
EINECS(EC#)231-469-1
Molecular FormulaC8H11 N O
Molecular Weight137.20
Appearancewhite solid
refractive index1.558-1.56
Hazard
Xi
Risk R36/37/38
Safety
Poison by intraperitoneal and intravenous routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
Hazard Codes:
Xi,
C
Risk Statements:
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
guinea pig |
LDLo |
subcutaneous |
1gm/kg (1000mg/kg) |
|
"Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 73, 1948. |
mouse |
LD50 |
intraperitoneal |
250mg/kg (250mg/kg) |
|
National Technical Information Service. Vol. AD691-490, |
mouse |
LDLo |
subcutaneous |
686mg/kg (686mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 47, Pg. 96, 1934. |
mouse |
LDLo |
unreported |
1100mg/kg (1100mg/kg) |
AUTONOMIC NERVOUS SYSTEM: SYMPATHOMIMETIC |
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 153, Pg. 161, 1930. |
rabbit |
LDLo |
intravenous |
23mg/kg (23mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 47, Pg. 96, 1934. |
Carcinogenicity of 2-Hydroxyphenethylamine (CAS NO.7568-93-6) hasn't been listed as a carcinogen by NTP, IARC,ACGIH, or CA Prop 65. And its toxicological properties have not been fully investigated.You can see actual entry in RTECS for complete information.