75706-12-6|LeflunomideProducts Supply - Chemical intermediates Network

Leflunomide cas no:75706-12-6

Synonyms: 4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl)-;N-(4-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide;Leflunomidum [INN-Latin];sell leflunomide;5-methyl-N-[4-(trifluoromethyl)phenyl]oxazole-4-carboxamide;5-Methylisoxazole-4-(4-trifluoromethyl) carboxanilide;Leflunamide;Isoxazole-4-carboxamide, 5-methyl-N-[4-(trifluoromethyl)phenyl]-;5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide;Arava;Leflunomida [INN-Spanish];

Identification

NameLeflunomide
CAS75706-12-6
Synonyms4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl)-;N-(4-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide;Leflunomidum [INN-Latin];sell leflunomide;5-methyl-N-[4-(trifluoromethyl)phenyl]oxazole-4-carboxamide;5-Methylisoxazole-4-(4-trifluoromethyl) carboxanilide;Leflunamide;Isoxazole-4-carboxamide, 5-methyl-N-[4-(trifluoromethyl)phenyl]-;5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide;Arava;Leflunomida [INN-Spanish];
Molecular FormulaC₁₂H₉F₃N₂O₂
Molecular Weight270.21

Chemical Properties

Appearanceoff white crystalline solid
storage temp2-8°C

Safety Data

Hazard Xn:Harmful
Risk R22;R36/37/38
Safety

Hazard Codes:? Harmful Xn,Xi
Risk Statements: 22-36/37/38?
R22:Harmful if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
?S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: NY2354200

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	185mg/kg (185mg/kg)	?	United States Patent Document. Vol. #5494911,
mouse	LD50	oral	445mg/kg (445mg/kg)	?	United States Patent Document. Vol. #5494911,
rat	LD50	intraperitoneal	170mg/kg (170mg/kg)	?	United States Patent Document. Vol. #5494911,
rat	LD50	oral	235mg/kg (235mg/kg)	?	United States Patent Document. Vol. #5494911,

supplier list

Hangzhou Starshine Pharmaceutical Co., LTD: Tel:86-571-8696517; Address: Fengqi East Road, Hangzhou, China.

IFFECT CHEMPHAR CO., LTD.: Tel:86-25-84679300; Address: 509, FuXin International Building, No.359 HongWu R

Chuming Pharmaceutical Limited: Tel:; Address: 9th Fl.,Garden Building, Jiuzhou Ave. No.1083, Zhuhai,China

THYKN (INDIA) INTERNATIONAL: Tel:+91-22-67033666 (3 lines); Address: 202, Kuntal, Mody Estate, Nr.Pipeline, LBS Road, Ghatkopar (West), Mumbai - 400086, India

Changzhou Yabang Pharmaceutical Co., LTD: Tel:; Address: 6# Liangchang Donglu, Jintan, Changzhou, Jiangsu, China

Jiangsu Guotai International Group: Tel:; Address: 10-11/F, Guotai Bldg, 43 Renmin Road, Zhangjiagang, Jiangsu Province, China 215600.

Prism International: Tel:; Address:

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

Changzhou Leo Chemical Co.,Ltd.: Tel:; Address: NO. 538 XINQING ROAD, XINZHA TOWN, ZHONGLOU DISTRICT, CHANGZHOU, JIANGSU, CHINA

Yancheng Lvye Chemical Co., Ltd.: Tel:0086-515-88710661; Address: No.62, kalfang Avenue, Yancheng Jiangsu, CHINA

Changzhou Qianyao Pharmaceutical Raw Material Factory: Tel:86-519-82869185; Address: Baita Town,Jintan Changzhou,Jiangsu

Wudi Reaction Pharma&Chemical Co.,Ltd.: Tel:; Address: Xinhai Industrial Park, Wudi County, Shandong Province, China

FAITH EAGLE (LABORATORY) LTD.: Tel:(+86-755) 82851290; Address: 15A/F.,Block A,World Trade Plaza,8# FuHong Rd., FuTian,Shenzhen, China

SINOCO CHEMICAL CO., LIMITED: Tel:+86-571-81956191, 81956192; Address: 425 Ruiqi Mansion Moganshan Road , Hangzhou 310011 China.

Lianyungang Jiafu International Trade Co., Ltd.: Tel:+86-518-85319777,85319779; Address: 10/F, A, Longhe Mansion, 6 Cangwulu, Xinpu district, Lianyungang, Jiangsu, China

Leflunomide cas no:75706-12-6

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