75706-12-6|LeflunomideProducts Supply - Chemical intermediates Network

Leflunomide cas no:75706-12-6

Synonyms: 4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl)-;N-(4-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide;Leflunomidum [INN-Latin];sell leflunomide;5-methyl-N-[4-(trifluoromethyl)phenyl]oxazole-4-carboxamide;5-Methylisoxazole-4-(4-trifluoromethyl) carboxanilide;Leflunamide;Isoxazole-4-carboxamide, 5-methyl-N-[4-(trifluoromethyl)phenyl]-;5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide;Arava;Leflunomida [INN-Spanish];

Identification

NameLeflunomide
CAS75706-12-6
Synonyms4-Isoxazolecarboxamide, 5-methyl-N-(4-(trifluoromethyl)phenyl)-;N-(4-Trifluoromethylphenyl)-5-methylisoxazole-4-carboxamide;Leflunomidum [INN-Latin];sell leflunomide;5-methyl-N-[4-(trifluoromethyl)phenyl]oxazole-4-carboxamide;5-Methylisoxazole-4-(4-trifluoromethyl) carboxanilide;Leflunamide;Isoxazole-4-carboxamide, 5-methyl-N-[4-(trifluoromethyl)phenyl]-;5-Methylisoxazole-4-carboxylic acid (4-trifluoromethyl)anilide;Arava;Leflunomida [INN-Spanish];
Molecular FormulaC₁₂H₉F₃N₂O₂
Molecular Weight270.21

Chemical Properties

Appearanceoff white crystalline solid
storage temp2-8°C

Safety Data

Hazard Xn:Harmful
Risk R22;R36/37/38
Safety

Hazard Codes:? Harmful Xn,Xi
Risk Statements: 22-36/37/38?
R22:Harmful if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
?S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: NY2354200

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	185mg/kg (185mg/kg)	?	United States Patent Document. Vol. #5494911,
mouse	LD50	oral	445mg/kg (445mg/kg)	?	United States Patent Document. Vol. #5494911,
rat	LD50	intraperitoneal	170mg/kg (170mg/kg)	?	United States Patent Document. Vol. #5494911,
rat	LD50	oral	235mg/kg (235mg/kg)	?	United States Patent Document. Vol. #5494911,

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CNCCC SICHUAN IMPORT/EXPORT CO.,LTD.: Tel:; Address: 8C Ruili, Palm Garden, 153 KeHua North Rd, Chengdu,Sichuan, P.R.China

IFFECT CHEMPHAR CO., LTD.: Tel:86-25-84679300; Address: 509, FuXin International Building, No.359 HongWu R

Changzhou ComWin Fine Chemicals Co.,Ltd.: Tel:; Address: 24th Floor, Jiaye International Commercial Plaza, 99 Yanling West Road, Changzhou, Jiangsu, China

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Fine Chem Trading LTD: Tel:+44-079-7062-7591; Address: PO Box 292, Greenford, UB6 9ZL, England

ZunAn Commerce & Industrial Co., Ltd.: Tel:锛?86-755-82910159, 82910995,82910996; Address: Room 3007, United Plaza A, Binhe Road 5022, Shenzhen, P.R.China

Changzhou Yabang Pharmaceutical Co., LTD: Tel:; Address: 6# Liangchang Donglu, Jintan, Changzhou, Jiangsu, China

Jiangsu Guotai International Group: Tel:; Address: 10-11/F, Guotai Bldg, 43 Renmin Road, Zhangjiagang, Jiangsu Province, China 215600.

Prism International: Tel:; Address:

Aliapharm: Tel:+49 69 971412-0; Address: AliaPharm GmbH Frankfurt Niedenau 49 60325 Frankfurt / Main

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

Changzhou Qianyao Pharmaceutical Raw Material Factory: Tel:86-519-82869185; Address: Baita Town,Jintan Changzhou,Jiangsu

Wudi Reaction Pharma&Chemical Co.,Ltd.: Tel:; Address: Xinhai Industrial Park, Wudi County, Shandong Province, China

Lianyungang Jiafu International Trade Co., Ltd.: Tel:+86-518-85319777,85319779; Address: 10/F, A, Longhe Mansion, 6 Cangwulu, Xinpu district, Lianyungang, Jiangsu, China

Vinchem, Inc.: Tel:+1-973-6354841; Address: Vinchem, Inc. 301 Main Street PO box 639 Chatham, NJ 07928

Leflunomide cas no:75706-12-6

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