3-Pyridinemethanol, a-[3-(methylnitrosoamino)propyl]- cas no:76014-81-8

Name3-Pyridinemethanol, a-[3-(methylnitrosoamino)propyl]-
CAS76014-81-8
Synonyms(?à)-NNAL;4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol;4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)butan-1-ol; NNAL; Racemic4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol; Racemic NNAL
Molecular FormulaC10H15 N3 O2
Molecular Weight209.28

refractive index1.557
storage temp2-8°C

Safety

Questionable carcinogen with carcinogenic and neoplastic data. When heated to decomposition it emits toxic vapors of NO_x.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UT5014750

CHEMICAL NAME :

3-Pyridinemethanol, alpha-(3-(methylnitrosoamino)propyl)-

CAS REGISTRY NUMBER :

76014-81-8

LAST UPDATED :

199507

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C10-H15-N3-O2

MOLECULAR WEIGHT :

209.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

41850 ug/kg

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :

CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 11,1017,1990

TYPE OF TEST :

TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

105 mg/kg/7W-I

TOXIC EFFECTS :

Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

REFERENCE :

CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 71,25,1993