76144-81-5|MildronateProducts Supply - Chemical intermediates Network

Mildronate cas no:76144-81-5

Synonyms: 3-(trimethylammonioamino)propanoate;Meldonium [INN];Hydrazinium,2-(2-carboxyethyl)-1,1,1- trimethyl-,inner salt;2-(2-Carboxyethyl)-1,1,1-trimethylhydrazinium hydroxide inner salt;Quaterin;Kvaterin;Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, hydroxide, inner salt;MET 88;Meldonium;

Identification

NameMildronate
CAS76144-81-5
Synonyms3-(trimethylammonioamino)propanoate;Meldonium [INN];Hydrazinium,2-(2-carboxyethyl)-1,1,1- trimethyl-,inner salt;2-(2-Carboxyethyl)-1,1,1-trimethylhydrazinium hydroxide inner salt;Quaterin;Kvaterin;Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, hydroxide, inner salt;MET 88;Meldonium;
Molecular FormulaC₆H₁₄N₂O₂
Molecular Weight146.19

Chemical Properties

AppearanceWhite crystalline powder
refractive index1.598
storage tempRefrigerator

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD	intraperitoneal	> 4gm/kg (4000mg/kg)	?	Eksperimental'naya i Klinicheskaya Farmakoterapiya. Vol. 19, Pg. 67, 1991.
mouse	LD50	intraperitoneal	7850mg/kg (7850mg/kg)	?	British UK Patent Application. Vol. #2105992,
mouse	LD50	intravenous	4430mg/kg (4430mg/kg)	?	British UK Patent Application. Vol. #2105992,
mouse	LD50	oral	18500mg/kg (18500mg/kg)	?	Eksperimental'naya i Klinicheskaya Farmakoterapiya. Vol. 19, Pg. 67, 1991.
rabbit	LDLo	intravenous	8gm/kg (8000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Eksperimental'naya i Klinicheskaya Farmakoterapiya. Vol. 19, Pg. 67, 1991.
rat	LD50	intraperitoneal	12gm/kg (12000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Eksperimental'naya i Klinicheskaya Farmakoterapiya. Vol. 19, Pg. 67, 1991.
rat	LD50	oral	> 20gm/kg (20000mg/kg)	?	Eksperimental'naya i Klinicheskaya Farmakoterapiya. Vol. 19, Pg. 67, 1991.

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Mildronate cas no:76144-81-5

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