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Cobalt chloride cas no:7646-79-9

Synonyms: Cobalt(2+) chloride;Cobalt(II) chloride;Cobaltous dichloride;Dichlorocobalt;NSC 51149;Cobaltchloride;Cobalt dichloride;Cobalt dichloride (CoCl2);Cobaltous chloride;

Identification
NameCobalt chloride
CAS7646-79-9
SynonymsCobalt(2+) chloride;Cobalt(II) chloride;Cobaltous dichloride;Dichlorocobalt;NSC 51149;Cobaltchloride;Cobalt dichloride;Cobalt dichloride (CoCl2);Cobaltous chloride;
EINECS(EC#)231-589-4
Molecular FormulaCl2Co
Molecular Weight129.83
Chemical Properties
AppearanceBLUE HYGROSCOPIC POWDER TURNS PINK ON EXPOSURE TO AIR AND MOISTURE
storage temp2-8°C
Sensitive Hygroscopic
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass8
Safety Data

Hazard T: Toxic;N: Dangerous for the environment;
Risk R22;R42/43;R49;R50/53
Safety

Hazard Codes?of Cobaltous chloride (CAS NO.7646-79-9):?ToxicT,DangerousN
Risk Statements: 49-42/43-52/53-50-22?
R49: May cause cancer by inhalation.?
R42/43: May cause sensitization by inhalation and skin contact.?
R52/53: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R50: Very toxic to aquatic organisms.?
R22: Harmful if swallowed.
Safety Statements:?53-23-36/37-45-60-61-22?
S53: Avoid exposure - obtain special instructions before use.?
S23: Do not breathe vapour.?
S36/37: Wear suitable protective clothing and gloves.?
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S60: This material and its container must be disposed of as hazardous waste.?
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.?
S22: Do not breathe dust.
RIDADR:?UN 2923 8/PG 3
WGK Germany: 2
RTECS: GF9800000
F: 9-21
HazardClass: 8
PackingGroup: III
Poison experimentally by ingestion, skin contact, intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic to humans by ingestion. Human systemic effects by ingestion: anorexia, goiter (increased thyroid size), and weight loss. Experimental teratogenic and reproductive effects.? When heated to decomposition it emits toxic fumes of Cl?.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child LDLo oral 1500mg/kg (1500mg/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 182, 1969.
child TDLo oral 48mg/kg (48mg/kg) BEHAVIORAL: ANOREXIA (HUMAN

ENDOCRINE: THYROID WEIGHT (GOITER)
JAMA, Journal of the American Medical Association. Vol. 157, Pg. 117, 1955.
dog LDLo intravenous 36mg/kg (36mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
guinea pig LD50 oral 55mg/kg (55mg/kg) ? Hygiene and Sanitation Vol. 36(1-3), Pg. 277, 1971.
guinea pig LDLo intraperitoneal 165mg/kg (165mg/kg) ? Archives of Environmental Health. Vol. 11, Pg. 201, 1965.
guinea pig LDLo skin 165mg/kg (165mg/kg) ? Archives of Environmental Health. Vol. 11, Pg. 201, 1965.
man TDLo oral 1042mg/kg/13W (1042mg/kg) SENSE ORGANS AND SPECIAL SENSES: OPTIC NERVE NEUROPATHY: EYE

SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE
Israel Journal of Medical Sciences. Vol. 8, Pg. 61, 1972.
mouse LD50 intraperitoneal 49mg/kg (49mg/kg) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 244, Pg. 17, 1962.
mouse LD50 intravenous 23300ug/kg (23.3mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
mouse LD50 oral 80mg/kg (80mg/kg) ? Hygiene and Sanitation Vol. 36(1-3), Pg. 277, 1971.
rabbit LDLo oral 1272mg/kg (1272mg/kg) ? Scottish Medical and Surgical Journal. Vol. 26, Pg. 131, 1826.
rabbit LDLo subcutaneous 200mg/kg (200mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat LD50 intraperitoneal 17402ug/kg (17.402mg/kg) ? Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 48, Pg. 143, 1959.
rat LD50 intravenous 4300ug/kg (4.3mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.
rat LD50 oral 80mg/kg (80mg/kg) ? Hygiene and Sanitation Vol. 36(1-3), Pg. 277, 1971.
rat LDLo skin 2gm/kg (2000mg/kg) ? Research and Consulting Company, Technical Reports. Vol. NOTOX1073/1335, Pg. 1988,

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