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Sodium Chloride cas no:7647-14-5

Synonyms: SALT; SEA SALT; TANKER FINE SALT; SODIUM STOCK SOLUTION; SODIUM STANDARD STOCK SOL; SODIUM CHLORIDE NATIVE; SODIUM CHLORIDE 2500 UMHO/

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Identification
NameSodium Chloride
CAS7647-14-5
SynonymsSALT; SEA SALT; TANKER FINE SALT; SODIUM STOCK SOLUTION; SODIUM STANDARD STOCK SOL; SODIUM CHLORIDE NATIVE; SODIUM CHLORIDE 2500 UMHO/
EINECS(EC#)231-598-3
Molecular FormulaNaCl
Molecular Weight58.44
Chemical Properties
Appearancecolourless crystals or white powder
refractive indexn20/D 1.378
storage tempStore in a cool, dry, well-ventilated area away from incompatible substances.
Sensitive Hygroscopic
Safety Data

Hazard Xi: Irritant;
Risk R36;R22
Safety Poison by intraperitoneal and intracervical routes. Moderately toxic by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Human systemic effects by ingestion: blood pressure increase. Human reproductive effects by intraplacental route: terminates pregnancy. Experimental reproductive effects. Human mutation data reported. A skin and eye irritant. When bulk sodium chloride is heated to high temperature, a vapor is emitted that is irritating, particularly to the eyes. Ingestion of large amounts of sodium chloride can cause irritation of the stomach. Improper use of salt tablets may produce this effect. Potentially explosive reaction with dichloromaleic anhydride + urea. Electrolysis of mixtures with nitrogen compounds may form the explosive nitrogen trichloride. Reaction with burning lithium forms the dangerously reactive sodium. The molten salt at 1100° reacts explosively with water. Violent reaction with BrF3. When heated to decomposition it emits toxic fumes of Cl- and Na2O.
Hazard Codes:?IrritantXi
The Risk Statements information of: Sodium chloride:
22:? Harmful if swallowed
36:? Irritating to the eyes
36/37/38:? Irritating to eyes, respiratory system and skin
The Safety Statements information of? Sodium chloride:
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:? Wear suitable protective clothing
24/25:? Avoid contact with skin and eyes
WGK Germany:? 1
F:? 3-10
HS Code 3822 00 00

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 2gm/kg (2000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 21, Pg. 119, 1886.
guinea pig LDLo intraarterial 300mg/kg (300mg/kg) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo intravenous 300mg/kg (300mg/kg) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo parenteral 300mg/kg (300mg/kg) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928.
guinea pig LDLo subcutaneous 2160mg/kg (2160mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
human TDLo oral 12357mg/kg/23 (12357mg/kg) VASCULAR: BP ELEVATION NOT CHARACTERIZED IN AUTONOMIC SECTION American Journal of Digestive Diseases. Vol. 21, Pg. 180, 1954.
man LDLo oral 1gm/kg (1000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)		 Mayo Clinic Proceedings. Vol. 65, Pg. 1587, 1990.
mouse LD50 intracervical 131mg/kg (131mg/kg) ? Tohoku Yakka Daigaku Kenkyu Nempo. Annual Report of the Tohoku College of Pharmacy. Vol. 27, Pg. 131, 1980.
mouse LD50 intraperitoneal 2602mg/kg (2602mg/kg) ? Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.
mouse LD50 intravenous 645mg/kg (645mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 445, 1957.
mouse LD50 oral 4gm/kg (4000mg/kg) ? Farmaco, Edizione Pratica. Vol. 27, Pg. 19, 1972.
mouse LD50 subcutaneous 3gm/kg (3000mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 445, 1957.
rabbit LD50 skin > 10gm/kg (10000mg/kg) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 20-3/1971,
rabbit LDLo intravenous 1100mg/kg (1100mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)

CARDIAC: OTHER CHANGES		 Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 21, Pg. 119, 1886.
rabbit LDLo oral 8gm/kg (8000mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat LC50 inhalation > 42gm/m3/1H (42000mg/m3) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 20-3/1971,
rat LD50 oral 3gm/kg (3000mg/kg) ? Toxicology and Applied Pharmacology. Vol. 20, Pg. 57, 1971.
rat LDLo subcutaneous 3500mg/kg (3500mg/kg) BEHAVIORAL: IRRITABILITY Endocrinology Vol. 24, Pg. 523, 1939.

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