76648-01-6|5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R,3S)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-3-hydroxy-1-oxobutyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:1), (6R,7S)-Products Supply

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R,3S)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-3-hydroxy-1-oxobutyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:1), (6R,7S)- cas no:76648-01-6

Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R,3S)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-3-hydroxy-1-oxobutyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, (6R,7S)- (9CI);Cefbuperazonesodium;Keiperazon;T 1982;

Identification

Name5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R,3S)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-3-hydroxy-1-oxobutyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:1), (6R,7S)-
CAS76648-01-6
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R,3S)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-3-hydroxy-1-oxobutyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,monosodium salt, (6R,7S)- (9CI);Cefbuperazonesodium;Keiperazon;T 1982;
Molecular FormulaC₂₂H₂₈N₉NaO₉S₂
Molecular Weight649.63

Safety Data

Safety Experimental reproductive effects. An experimental teratogen. When heated to decomposition it emits toxic fumes of SOx, NOx and Na2O.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 8gm/kg (8000mg/kg)		Chemotherapy Vol. 30(Suppl,
mouse	LD50	intraperitoneal	> 10gm/kg (10000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 30(Suppl,
mouse	LD50	intravenous	> 10gm/kg (10000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA	Chemotherapy Vol. 30(Suppl,
mouse	LD50	oral	> 10gm/kg (10000mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 30(Suppl,
mouse	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Chemotherapy Vol. 30(Suppl,
rat	LD50	intraperitoneal	> 10gm/kg (10000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 30(Suppl,
rat	LD50	intravenous	9550mg/kg (9550mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: ATAXIA	Chemotherapy Vol. 30(Suppl,
rat	LD50	oral	> 10gm/kg (10000mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Chemotherapy Vol. 30(Suppl,
rat	LD50	subcutaneous	> 10gm/kg (10000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Chemotherapy Vol. 30(Suppl,

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China Langchem Inc.: Tel:+86-(21)-58956006; Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203,

Beijing Zezhongkang pharmaceutical Co,.Ltd: Tel:0086-01-86561835; Address: Dongfang Caifu Plaza 1601, street of Guangqumengnei,Chunwen distract,Beijing,China

shijiazhuang guizheng trade co.,ltd: Tel:86-312-18103315327; Address: east huaxia road pudong shanghai china

Jinan Haohua Industry Co., Ltd.: Tel:0086-531-58773055; Address: No.59 Gongye South RD

wuhan cillin chemical: Tel:+86-15527136576; Address: Wuhan city

Hainan Shunyuan Chemtech. Co., Ltd: Tel:+86-0898-68529231 68529232; Address: Hainan,china

lotuschem: Tel:852-29738324; Address: Rm. 907. JCD116 Wing Tuck Commercial Centre, 177-183 Wing Lok Street, Hong Kong

Kingland Chemicals Company Limited: Tel:+86-571-87211518,87229835; Address: Room No. 1806-1808, Jinfeng Mansion, No.281 Zhong He Zhong Road, Hangzhou, China.

Broad Pharmaceutical CO.,Ltd.: Tel:+86-10-5173 3671; Address: A3 Yihai building 14,Qinghua east road 16, Haidian District, Beijing , China

ALL PRO CORPORATION: Tel:86-532-82850205; Address: No.592, TONGHE ROAD, QINGDAO, CHINA

Atomole Scientific Co., Ltd.: Tel:+86-(27)-82261049; Address: No.5 Xie Chang Li, Suite 101, Flower Bridge 2nd Village, Wuhan, Hubei 430019,

Shanghai Mijiang Chemical Co., Ltd.: Tel:+86-(21)-64050366; Address: Room 607, Xuanrun international mansion, 1100#, Wuzhonglu, Shanghai 201103,

Beijing Nine Camp Medicine Technology Co., Ltd.: Tel:+86-(10)-8779-8750; Address: Hong Jiu Office Premises 627#, Pingle Yuan, Chaoyang District, Beijing,

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Zhiyu Biotechnology Co., Ltd.: Tel:+86-(512)-6279-1916; Address: Room A210, Century Finacial Tower, No.1 Suhua Road, Suzhou 215021,

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R,3S)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-3-hydroxy-1-oxobutyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:1), (6R,7S)- cas no:76648-01-6

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