Welcome to hiintermediates.com,intermediates trading platform
Home > products > Sodium fluoride

Sodium fluoride cas no:7681-49-4

Synonyms: Sodium fluoride 99% (ACS); Fluoride ion chromatography standard solution Fluka; Fluoride; Sodiumfluoridemetalsbasiswhitepowder; Sodiumfluorideopticalgradewhitextl; Sodium fluoride solution; Activity standard solution for fluoride electrode (100 ppm as fluoride); Natriumfluorid

Identification
NameSodium fluoride
CAS7681-49-4
SynonymsSodium fluoride 99% (ACS); Fluoride ion chromatography standard solution Fluka; Fluoride; Sodiumfluoridemetalsbasiswhitepowder; Sodiumfluorideopticalgradewhitextl; Sodium fluoride solution; Activity standard solution for fluoride electrode (100 ppm as fluoride); Natriumfluorid
EINECS(EC#)231-667-8
Molecular FormulaNaF
Molecular Weight41.99
Chemical Properties
Appearancewhite odorless powder or crystal
refractive index1.336
storage temp2-8°C
Sensitive Hygroscopic
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1
Safety Data

Hazard T:Toxic
Risk R25;R32;R36/38
Safety

Hazard Codes:?ToxicT
Risk Statements: 25-32-36/38?
R25 :Toxic if swallowed.?
R32:Contact with acid liberates very toxic gas.?
R36/38:Irritating to eyes and skin.
Safety Statements: 23-24/25-45-36-22?
S23:Do not breathe vapour.?
S24/25:Avoid contact with skin and eyes.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36:Wear suitable protective clothing.?
S22:Do not breathe dust.
RIDADR: UN 1690 6.1/PG 3
WGK Germany: 1
RTECS: WB0350000
F: 10
Hazard Note: Toxic/Hygroscopic
HazardClass: 6.1
PackingGroup: III
Human poison by ingestion. Experimental poison by ingestion, skin contact, intravenous, intraperitoneal, subcutaneous, and intramuscular routes. Human systemic effects: changes in teeth and supporting structures, cyanosis, diarrhea, EKG changes, fluid intake, headache, hypermotility, increased immune response, muscle weakness, musculo-skeletal changes, nausea or vomiting, paresthesia, ptosis (drooping of the eyelid from sympathetic innervation), respiratory depression, salivary gland changes, tremors. Experimental teratogenic and reproductive effects. Human mutation data reported. A corrosive irritant to skin, eyes, and mucous membranes. Questionable carcinogen with experimental tumorigenic data. It is very phytotoxic. When heated to decomposition it emits toxic fumes of F? and Na2O. Used in chemical cleaning, for fluoridation of drinking water, as a fungicide and insecticide. See also FLUORIDES.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 110mg/kg (110mg/kg) ? Archives of Environmental Contamination and Toxicology. Vol. 16, Pg. 483, 1987.
cat LDLo subcutaneous 14mg/kg (14mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1349, 1935.
dog LDLo intraperitoneal 50mg/kg (50mg/kg) ? U.S. Atomic Energy Commission, University of Rochester, Research and Development Reports. Vol. UR-154, Pg. 1951,
dog LDLo subcutaneous 155mg/kg (155mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1349, 1935.
domestic animals - goat/sheep LD50 oral 100mg/kg (100mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
New Zealand Veterinary Journal. Vol. 30, Pg. 199, 1982.
frog LDLo subcutaneous 448mg/kg (448mg/kg) ? Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 124, Pg. 133, 1937.
guinea pig LDLo subcutaneous 100mg/kg (100mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1349, 1935.
human LDLo oral 71mg/kg (71mg/kg) BEHAVIORAL: TREMOR

MUSCULOSKELETAL: CHANGES IN TEETH AND SUPPORTING STRUCTURES

MUSCULOSKELETAL: OTHER CHANGES
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 1361, 1989.
human LDLo oral 75mg/kg (75mg/kg) ? Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1033, 1966.
human TDLo intradermal 14ug/kg (0.014mg/kg) PERIPHERAL NERVE AND SENSATION: PARESTHESIS

IMMUNOLOGICAL INCLUDING ALLERGIC: INCREASED IMMUNE RESPONSE
Revue Medicale de Liege. Vol. 12, Pg. 408, 1957.
human TDLo oral 214ug/kg (0.214mg/kg) BEHAVIORAL: HEADACHE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Revue Medicale de Liege. Vol. 12, Pg. 408, 1957.
man TDLo oral 1662mg/kg (1662mg/kg) CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: NAUSEA OR VOMITING
JAMA, Journal of the American Medical Association. Vol. 222, Pg. 816, 1972.
monkey LD50 intravenous 26600ug/kg (26.6mg/kg) ? Acta Pharmacologica et Toxicologica. Vol. 22, Pg. 99, 1965.
mouse LD50 intraperitoneal 38mg/kg (38mg/kg) GASTROINTESTINAL: OTHER CHANGES

LIVER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 27, Pg. 237, 1982.
mouse LD50 intravenous 50830ug/kg (50.83mg/kg) GASTROINTESTINAL: OTHER CHANGES

LIVER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 27, Pg. 237, 1982.
mouse LD50 oral 57mg/kg (57mg/kg) ? Shika Gakuho. Journal of Dentistry. Vol. 80, Pg. 1519, 1980.
mouse LD50 subcutaneous 115ug/kg (0.115mg/kg) ? Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 68(3), Pg. 55P-74P, 1972.
mouse LDLo skin 300mg/kg (300mg/kg) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 183, Pg. 427, 1936.
rabbit LD50 oral 200mg/kg (200mg/kg) ? Journal of Economic Entomology. Vol. 61, Pg. 751, 1968.
rabbit LDLo subcutaneous 100mg/kg (100mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1349, 1935.
rat LD50 intraperitoneal 22mg/kg (22mg/kg) ? U.S. Atomic Energy Commission, University of Rochester, Research and Development Reports. Vol. UR-154, Pg. 1951,
rat LD50 intravenous 26mg/kg (26mg/kg) SENSE ORGANS AND SPECIAL SENSES: TUMORS: OLFACTION

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
Toxicology and Applied Pharmacology. Vol. 3, Pg. 278, 1961.
rat LD50 oral 52mg/kg (52mg/kg) ? National Technical Information Service. Vol. UR-3490-95,
rat LD50 subcutaneous 175mg/kg (175mg/kg) ? Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 411, 1968.
women LDLo oral 90mg/kg (90mg/kg) BEHAVIORAL: FLUID INTAKE

BEHAVIORAL: MUSCLE WEAKNESS

GASTROINTESTINAL: NAUSEA OR VOMITING
JAMA, Journal of the American Medical Association. Vol. 81, Pg. 811, 1923.
women LDLo oral 360mg/kg (360mg/kg) LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: NAUSEA OR VOMITING
JAMA, Journal of the American Medical Association. Vol. 100, Pg. 97, 1933.
women TDLo oral 7mg/kg (7mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
British Medical Journal. Vol. 1, Pg. 886, 1936.

supplier list

ABSCO Ltd
Tel:+44-1440-709709
Address: 42 Hollands Road, Haverhill, Suffolk, CB9 8SA, United Kingdom
China National Chemical Construction Shenzhen Com...
Tel:
Address: 5/F., Shenzhen International Trade Centre Building, 3002,Renminnan Rd., 518014,Shenzhen,China
Changshu Jinxing Chemical Co.,Ltd.
Tel:
Address: Mo Cheng Town,Chang Shu City
Chem-Impex International Inc.
Tel:+1-(630)-766-2112
Address: Corporate Office:, 935 N. Dillon Drive, Wood Dale, Illinois 60191,
Kunming Chemical & Mineral Co., Ltd
Tel:+86-(871)-8018510
Address: Room2702, 27/F, Meijing Building, Tobacco Road, Kunming, Yunnan,
Xinxiang Yellow River Fine Chemical Industry Co., Ltd.
Tel:+86-(373)-7278760
Address: Chengguan Town, Yuanyang County, Xinxiang, Henan 453500,
Seal Chemical Industries Private Limited
Tel:+91-(11)-26149800
Address: C - 8 / 2, Vasant Vihar, New Delhi, Delhi 110057,
Awishkar Chemical Industries
Tel:+91-(265)-2634050
Address: 250/1B, Magazine House, G. I. D. C., Makarpura, Vadodara, Gujarat,
Calstar Inc
Tel:+1-(310)-549-0900
Address: 445 Figueroa St., Wilmington, California 90744,
Shangrao Guangfu Pharmachem Co., Ltd.
Tel:+86-(793)-269-5777, 269-5807
Address: Lianhua Shan, Qingqiao, Yangkou Town, Guangfeng County, Shangrao, Jiangxi 334604,
ADVANCED TECH. & IND. CO., LTD.
Tel:86-23902293
Address: UNIT B, 1/F, CHEONG SHING IND. BLDG., 17 WALNUT ST., TAI KOK TSUI, KLN, HONG KONG
Tianjin Hongyuan Maoye Chem CO.,ltd
Tel:86-22-23591358
Address: Fukang Road, Nankai District Tianjin China
Yellow River Fine Chemical Industry Co.,Ltd.
Tel:0086-373-7278760
Address: Chengguan Town, Yuanyang County
Wuhan Fortuna Chemical Co., Ltd.
Tel:0086-27-59207850
Address: A2705,Dong Yi Shi Qu,129# XinHua Road
Wuhan Senwayer Century chemical Co.,Ltd
Tel:86-27-59009407
Address: 20#Xudong Street,Wuhan China

Home   |   About Us   |   Service   |   Links   |   Add to  Favorite

Copyright©2011 HiIntermediates ICP: B2-20090288 浙ICP备09045134号-49
Tel: +86-0571-89739792