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1,2-Benzenediol,4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]- cas no:7683-59-2

Synonyms: Benzylalcohol, 3,4-dihydroxy-a-[(isopropylamino)methyl]- (8CI); (?à)-Isoprenaline; (?à)-Isoproterenol;1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol; 3,4-Dihydroxy-a-[(isopropylamino)methyl]benzylalcohol; A 21; Aludrin; Aludrine; Asiprenol; Asmalar; Assiprenol; Bellasthman;DL(?à)-Isoproterenol;DL-Isopropylnorepinephrine; DL-Isoproterenol; Epinephrine isopropyl homolog;ICI 46399; Isonorin; Isoprenalin; Isoprenaline; Isopropydrin;Isopropylaminomethyl(3,4-dihydroxyphenyl)carbinol; Isopropylarterenol;Isopropylnoradrenaline; Isopropylnorepinephrine; Isoproterenol; Isorenin;Isupren; Lomupren; N-Isopropyl-b-dihydroxyphenyl-b-hydroxyethylamine; N-Isopropylnoradrenaline; N-Isopropylnorepinephrine;NSC 33791; NSC 9975; Neo-Epinine; Neodrenal; Norisodrine; Racemic isoprenaline;Racemic isoproterenol; Respifral; Vapo-N-Iso; dl-Isadrine; dl-Isoprenaline; dl-Isopropylnoradrenaline;dl-Isoproterenol; dl-N-Isopropylnoradrenaline; a-(Isopropylaminomoethyl)protocatechuyl alcohol

Identification
Name1,2-Benzenediol,4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-
CAS7683-59-2
SynonymsBenzylalcohol, 3,4-dihydroxy-a-[(isopropylamino)methyl]- (8CI); (?à)-Isoprenaline; (?à)-Isoproterenol;1-(3,4-Dihydroxyphenyl)-2-(isopropylamino)ethanol; 3,4-Dihydroxy-a-[(isopropylamino)methyl]benzylalcohol; A 21; Aludrin; Aludrine; Asiprenol; Asmalar; Assiprenol; Bellasthman;DL(?à)-Isoproterenol;DL-Isopropylnorepinephrine; DL-Isoproterenol; Epinephrine isopropyl homolog;ICI 46399; Isonorin; Isoprenalin; Isoprenaline; Isopropydrin;Isopropylaminomethyl(3,4-dihydroxyphenyl)carbinol; Isopropylarterenol;Isopropylnoradrenaline; Isopropylnorepinephrine; Isoproterenol; Isorenin;Isupren; Lomupren; N-Isopropyl-b-dihydroxyphenyl-b-hydroxyethylamine; N-Isopropylnoradrenaline; N-Isopropylnorepinephrine;NSC 33791; NSC 9975; Neo-Epinine; Neodrenal; Norisodrine; Racemic isoprenaline;Racemic isoproterenol; Respifral; Vapo-N-Iso; dl-Isadrine; dl-Isoprenaline; dl-Isopropylnoradrenaline;dl-Isoproterenol; dl-N-Isopropylnoradrenaline; a-(Isopropylaminomoethyl)protocatechuyl alcohol
EINECS(EC#)231-687-7
Molecular FormulaC11H17 N O3
Molecular Weight247.72
Chemical Properties
Appearancewhite crystalline powder
Safety Data

Hazard UN NO.
Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects by intramuscular route: increased pulse and cardiac rate. A bronchodilator. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
 


Toxicity
1.    

oms-rat-par 100 mg/kg

    BEXBAN    Bulletin of Experimental Biology and Medicine. Translation of BEBMAE. 94 (1982),1458.
2.    

dns-mus-ipr 341 mg/kg

    JCLBA3    Journal of Cell Biology. 56 (1973),605.
3.    

ims-hmn TDLo:14 µg/kg:CVS

    KLWOAZ    Klinische Wochenscrift. 19 (1940),1303.
4.    

orl-rat LD50:355 mg/kg

    USXXAM    United States Patent Document. (Commissioner of Patents and Trademarks, Washington, DC 20231) #4026897 .
5.    

ipr-rat LDLo:100 mg/kg

    FCTXAV    Food and Cosmetics Toxicology. 3 (1965),597.
6.    

scu-rat LD50:600 µg/kg

    TOXID9    Toxicologist. 4 (1984),77.
7.    

ivn-rat LD50:57 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 16 (1970),303.
8.    

orl-mus LD50:450 mg/kg

    27ZIAQ    Drug Dosages in Laboratory Animals-A Handbook C.D. Barnes andL.G. Eltherington,Berkeley, CA.: Univ. of California Press,1973,139.
9.    

ipr-mus LD50:440 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 164 (1968),290.
10.    

scu-mus LD50:400 mg/kg

    ARZNAD    Arznei

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