Camptothecine cas no:7689-03-4
Synonyms: 4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (+)-Camptothecin; Camptothecin, Camptotheca acuminata; 4-Ethyl-4-hydroxy-1H-pyrano-[3,4:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Camptothecin,95%; Camptothecin; 4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Camptothecin
NameCamptothecine
CAS7689-03-4
Synonyms4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (+)-Camptothecin; Camptothecin, Camptotheca acuminata; 4-Ethyl-4-hydroxy-1H-pyrano-[3,4:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Camptothecin,95%; Camptothecin; 4-Ethyl-4-hydroxy-1H-pyrano-[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; Camptothecin
EINECS(EC#)444-280-6
Molecular FormulaC20H16N2O4
Molecular Weight348.36
Appearancelight yellow crystal powde
refractive index1.787
storage temp2-8°C
Hazard T:Toxic;
Risk R25
Safety
Safety Information of Camptothecine (CAS NO.7689-03-4):
Hazard Codes: 
T,
Xi,
Xn
Risk Statements:36/37/38-25-20/21/22
36/37/38:Irritating to eyes, respiratory system and skin
25:Toxic if swallowed
20/21/22:Harmful by inhalation, in contact with skin and if swallowed
Safety Statements:45-36/37/39-26-36
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:Wear suitable protective clothing
RIDADR:UN 1544 6.1/PG 3
WGK Germany:3
RTECS Note:UQ0492000
Hazard Note:Irritant
Poison by intravenous and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also CAMPTOTHECIN, SODIUM SALT.
| 1. |
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dnd-omi 100 mg/L/30M
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NATUAS Nature. 248 (1974),226. |
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dnd-hmn:hla 20 µmol/L
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CNREA8 Cancer Research. 33 (1973),2834. |
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dni-hmn:hla 5 µmol/L
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HXPHAU Handbuch der Experimentellen Pharmakologie. 38 (Pt 2),(1975),649. |
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oms-hmn:hla 5 µmol/L
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HXPHAU Handbuch der Experimentellen Pharmakologie. 38 (Pt 2),(1975),649. |
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oms-mus:lym 1 mg/L
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BCPCA6 Biochemical Pharmacology. 21 (1972),1977. |
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dni-ckn:emb 500 µg/L
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CJBIAE Canadian Journal of Biochemistry. 55 (1977),1180. |
| 7. |
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ipr-mus LD50:64 mg/kg
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CNREA8 Cancer Research. 39 (1979),2204. |
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ivn-mus LD50:38 mg/kg
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NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 . |
