Benzeneacetonitrile, a-[2-(dimethylamino)propyl]-a-(1-methylethyl)- cas no:77-51-0

NameBenzeneacetonitrile, a-[2-(dimethylamino)propyl]-a-(1-methylethyl)-
CAS77-51-0
SynonymsValeronitrile,4-(dimethylamino)-2-isopropyl-2-phenyl- (6CI,7CI,8CI); 3-Cyano-5-dimethylamino-3-phenyl-2-methylhexane;4-Dimethylamino-2-isopropyl-2-phenylvaleronitrile; Aprecon; Dimyril; Isoaminil;Isoaminile; Nullatuss; a-(b-Dimethylaminopropyl)-a-isopropylphenylacetonitrile; a-Isopropyl-a-(2-dimethylaminopropyl)phenylacetonitrile
EINECS(EC#)201-033-5
Molecular FormulaC16H24 N2
Molecular Weight244.42

refractive index1.504

Safety

Poison by intraperitoneal and subcutaneous routes. See also NITRILES. When heated to decomposition it emits very toxic fumes of NO_x and CN⁻.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	48400ug/kg (48.4mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 323, 1968.
mouse	LD50	intraperitoneal	77mg/kg (77mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 323, 1968.
mouse	LD50	intravenous	55mg/kg (55mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 323, 1968.
mouse	LD50	subcutaneous	127mg/kg (127mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ATAXIA	Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 323, 1968.
mouse	LDLo	oral	378mg/kg (378mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 323, 1968.