77-67-8|2,5-Pyrrolidinedione,3-ethyl-3-methyl-Products Supply

2,5-Pyrrolidinedione,3-ethyl-3-methyl- cas no:77-67-8

Synonyms: Succinimide,2-ethyl-2-methyl- (6CI,7CI,8CI); (?à)-Ethosuximide; 2-Ethyl-2-methylsuccinimide; 2-Methyl-2-ethylsuccinimide;3-Ethyl-3-methylpyrrolidine-2,5-dione; 3-Ethyl-3-methylsuccinimide;3-Methyl-3-ethylpyrrolidine-2,5-dione; 3-Methyl-3-ethylsuccinimide; Atysmal;C.I. 366; CN 10395; Capitus; Emeside; Epileo Petitmal; Ethosuxide;Ethosuximide; Ethymal; Etosuximid; H 940; Mesentol; NSC 64013; PM 671; Pemal;Peptinimid; Petinimid; Petnidan; Piknolepsin; Pyknolepsinum; Ronton; Simatin;Succimal; Succimitin; Suxilep; Suximal; Suxinutin; Zarodan; Zarondan;Zarondan-Saft; Zarontin; a-Ethyl-a-methylsuccinimide;a-Methyl-a-ethylsuccinimide

Identification

Name2,5-Pyrrolidinedione,3-ethyl-3-methyl-
CAS77-67-8
SynonymsSuccinimide,2-ethyl-2-methyl- (6CI,7CI,8CI); (?à)-Ethosuximide; 2-Ethyl-2-methylsuccinimide; 2-Methyl-2-ethylsuccinimide;3-Ethyl-3-methylpyrrolidine-2,5-dione; 3-Ethyl-3-methylsuccinimide;3-Methyl-3-ethylpyrrolidine-2,5-dione; 3-Methyl-3-ethylsuccinimide; Atysmal;C.I. 366; CN 10395; Capitus; Emeside; Epileo Petitmal; Ethosuxide;Ethosuximide; Ethymal; Etosuximid; H 940; Mesentol; NSC 64013; PM 671; Pemal;Peptinimid; Petinimid; Petnidan; Piknolepsin; Pyknolepsinum; Ronton; Simatin;Succimal; Succimitin; Suxilep; Suximal; Suxinutin; Zarodan; Zarondan;Zarondan-Saft; Zarontin; a-Ethyl-a-methylsuccinimide;a-Methyl-a-ethylsuccinimide
EINECS(EC#)201-048-7
Molecular FormulaC7H11 N O2
Molecular Weight141.19

Chemical Properties

storage tempRefrigerator

Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Safety Information of Ethosuximide (CAS NO.77-67-8):
Hazard Codes: Xn Harmful
Risk Statements: 22
R22:Harmful if swallowed
Safety Statements: 36
S36:Wear suitable protective clothing
WGK Germany: 3
RTECS: WN2800000
Moderately toxic by ingestion, intravenous, subcutaneous, and intraperitoneal routes. Experimental teratogenic and reproductive effects. Mutation data reported. An anticonvulsant. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

1.	cyt-hmn:lyms 30 mg/L	MUREAV Mutation Research. 204 (1988),623.
2.	orl-rat TDLo:66,600 µg/kg (6-14D preg):REP	40YJAX Evaluation of Embryotoxicity, Mutagenicity and Carcinogenicity Risks In New Drugs Benesova, O., et al., eds.,Prague, Czechoslovakia.: Univerzita Karlova,1970,59.
3.	orl-mus LD50:1530 mg/kg	EPILAK Epilepsia. 4 (4)(1963),66.
4.	ipr-mus LD50:1752 mg/kg	EPILAK Epilepsia. 29 (1988),198.
5.	scu-mus LD50:1810 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),117.
6.	ivn-mus LD50:780 mg/kg	NEPHBW Neuropharmacology. 24 (1985),427.

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2,5-Pyrrolidinedione,3-ethyl-3-methyl- cas no:77-67-8

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