Thiophene,2,5-dihydro-, 1,1-dioxide cas no:77-79-2
Synonyms: 2,5-Dihydrothiophen-1,1-dioxide;2,5-Dihydrothiophene 1,1-dioxide; 2,5-Dihydrothiophene S,S-dioxide;2,5-Dihydrothiophene dioxide; 2,5-Dihydrothiophene sulfone; 3-Sulfolene;Butadiene sulfone; NSC 48532; NSC 56373; Sulfolene; Sulpholene; b-Sulfolene
NameThiophene,2,5-dihydro-, 1,1-dioxide
CAS77-79-2
Synonyms2,5-Dihydrothiophen-1,1-dioxide;2,5-Dihydrothiophene 1,1-dioxide; 2,5-Dihydrothiophene S,S-dioxide;2,5-Dihydrothiophene dioxide; 2,5-Dihydrothiophene sulfone; 3-Sulfolene;Butadiene sulfone; NSC 48532; NSC 56373; Sulfolene; Sulpholene; b-Sulfolene
EINECS(EC#)201-059-7
Molecular FormulaC4H6 O2 S
Molecular Weight118.15
Appearancewhite crystals
Hazard UN
NO.
Risk R36/37/38
Safety
Moderately toxic by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of SOx.
Hazard Codes:
Xi
Risk Statements:
R41:Risk of serious damage to the eyes.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39:Wear suitable gloves and eye/face protection.
WGK Germany: 1
RTECS: XM9100000
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
1700mg/kg (1700mg/kg) |
|
Pharmaceutical Chemistry Journal Vol. 12, Pg. 1568, 1978. |
| mouse |
LD50 |
oral |
1600mg/kg (1600mg/kg) |
behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold gastrointestinal: change in structure or function of esophagus |
National Technical Information Service. Vol. OTS0534337, |
| rabbit |
LD50 |
skin |
> 5gm/kg (5000mg/kg) |
|
Toxicology and Applied Pharmacology. Vol. 28, Pg. 313, 1974. |
| rat |
LD50 |
intraperitoneal |
3200mg/kg (3200mg/kg) |
behavioral: somnolence (general depressed activity) behavioral: convulsions or effect on seizure threshold gastrointestinal: changes in structure or function of salivary glands |
National Technical Information Service. Vol. OTS0534337, |
| rat |
LD50 |
oral |
2547mg/kg (2547mg/kg) |
behavioral: tremor behavioral: ataxia gastrointestinal: changes in structure or function of salivary glands |
National Technical Information Service. Vol. OTS0546574, |
