Tris(hydroxymethyl)aminoethane cas no:77-86-1
Synonyms: 2-Amino-2-hydroxymethyl-1,3-propanediol; TRIS; Tromethamine; Tromethane; tris(hydroxyme.)aminomethane; trizma base; Trometamol; tri(hydroxymethyl)methylamine; Tris(hydroxymethyl) methylamine Tris buffer 99.8+ %; Trihydroxymethyl Aminomethane; Tris, Ultra Pure; Tris(hydroxymethyl)aminomethane, Ultra Pure; Tromethamine; Tris, Pure Tris(hydroxymethyl)aminomethane, Pure; Tris(hydroxymethyl)aminomethane, Technical Grade; Tris, Tissue Culture Tested Tris(hydroxymethyl)aminomethane, Tissue Culture Tested; Tris, Alcohol Free Tris(hydroxymethyl)aminomethane, Alcohol Free; Tris(hydroxymethyl)aminomethane, Ultra Pure, Molecular Biology Grade; Tris EDTA acetate buffer; TRIS; THAM; Trimethanolaminomethane; Tri(hydroxymethyl)aminomethane; Tris(hydroxymethyl)aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tris hydroxyl methyl amino methane
NameTris(hydroxymethyl)aminoethane
CAS77-86-1
Synonyms2-Amino-2-hydroxymethyl-1,3-propanediol; TRIS; Tromethamine; Tromethane; tris(hydroxyme.)aminomethane; trizma base; Trometamol; tri(hydroxymethyl)methylamine; Tris(hydroxymethyl) methylamine Tris buffer 99.8+ %; Trihydroxymethyl Aminomethane; Tris, Ultra Pure; Tris(hydroxymethyl)aminomethane, Ultra Pure; Tromethamine; Tris, Pure Tris(hydroxymethyl)aminomethane, Pure; Tris(hydroxymethyl)aminomethane, Technical Grade; Tris, Tissue Culture Tested Tris(hydroxymethyl)aminomethane, Tissue Culture Tested; Tris, Alcohol Free Tris(hydroxymethyl)aminomethane, Alcohol Free; Tris(hydroxymethyl)aminomethane, Ultra Pure, Molecular Biology Grade; Tris EDTA acetate buffer; TRIS; THAM; Trimethanolaminomethane; Tri(hydroxymethyl)aminomethane; Tris(hydroxymethyl)aminomethane; 2-Amino-2-(hydroxymethyl)-1,3-propanediol; Tris hydroxyl methyl amino methane
EINECS(EC#)201-064-4
Molecular FormulaC4H11NO3
Molecular Weight121.14
Appearancewhite crystalline powder
refractive index1.531
storage temp2-8°C
Sensitive Hygroscopic
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Hazard Xi:Irritant
Risk R36/37/38
Safety
Safety Information of Tromethamine (CAS NO.77-86-1):
Hazard Codes: Xi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
S37/39:Wear suitable gloves and eye/face protection.
HS Code 29221980
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intravenous |
1210mg/kg (1210mg/kg) |
? |
Acta Biologica et Medica Germanica. Vol. 17, Pg. 217, 1966. |
| rabbit |
LDLo |
oral |
1gm/kg (1000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: COMA |
Journal of Industrial Hygiene and Toxicology. Vol. 22, Pg. 315, 1940. |
| rat |
LD50 |
intravenous |
1800mg/kg (1800mg/kg) |
? |
Drugs in Japan Vol. -, Pg. 419, 1990. |
| rat |
LD50 |
oral |
5900mg/kg (5900mg/kg) |
? |
Bollettino Chimico Farmaceutico. Vol. 110, Pg. 653, 1971. |
