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Citric acid cas no:77-92-9

Synonyms: 2-Hydroxy-1,2,3-propanetricarboxylic acid; Citric acid, anhydrous, USP Grade 1,2,3-Propanetricarboxylic acid, 2 hydroxy-citric acid, anhydrous, USP Grade; Citric acid anhydrous; Citric acid anhydride

Identification
NameCitric acid
CAS77-92-9
Synonyms2-Hydroxy-1,2,3-propanetricarboxylic acid; Citric acid, anhydrous, USP Grade 1,2,3-Propanetricarboxylic acid, 2 hydroxy-citric acid, anhydrous, USP Grade; Citric acid anhydrous; Citric acid anhydride
EINECS(EC#)201-069-1
Molecular FormulaC6H8O7
Molecular Weight192.12
Chemical Properties
AppearanceWhite crystalline powder
refractive index1.493~1.509
storage tempStore at RT.
Sensitive Hygroscopic
Safety Data

Hazard Xi:Irritant
Risk R36/37/38
Safety

Safety Information about?Citric Acid Anhydrous (CAS NO: 77-92-9):
Hazard Codes: Xi, C
Risk Statements: 41-36/37/38-34
41:?Risk of serious damage to eyes?
36/37/38:?Irritating to eyes, respiratory system and skin?
34:?Causes burns
Safety Statements: 26-24/25-36/37/39-45
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
24/25: Avoid contact with skin and eyes?
36/37/39: Wear suitable protective clothing, gloves and eye/face protection?
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR:?UN 1789 8/PG 3
WGK Germany : 1
F: 9: Keep under nitrogen.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 903mg/kg (903mg/kg) ? Toxicology. Vol. 62, Pg. 203, 1990.
mouse LD50 intravenous 42mg/kg (42mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
mouse LD50 oral 5040mg/kg (5040mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

MUSCULOSKELETAL: OTHER CHANGES
Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 30, Pg. 25, 1971.
mouse LD50 subcutaneous 2700mg/kg (2700mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

MUSCULOSKELETAL: OTHER CHANGES
Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 30, Pg. 25, 1971.
rabbit LD50 intravenous 330mg/kg (330mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 65, 1948.
rabbit LDLo oral 7gm/kg (7000mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
Industrial and Engineering Chemistry. Vol. 15, Pg. 628, 1923.
rat LD50 intraperitoneal 290mg/kg (290mg/kg) ? Toksikologicheskii Vestnik. Vol. (5), Pg. 9, 1994.
rat LD50 oral 3gm/kg (3000mg/kg) ? Oyo Yakuri. Pharmacometrics. Vol. 43, Pg. 561, 1992.
rat LD50 subcutaneous 5500mg/kg (5500mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

MUSCULOSKELETAL: OTHER CHANGES
Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 30, Pg. 25, 1971.

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