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Ferrous sulfate cas no:7720-78-7

Synonyms: Combiron;Copperas;Duretter;Duroferon;Exsiccated ferrous sulfate;Exsiccated ferroussulphate;Feofol Spansule;Feosol;Feospan;Fer-In-Sol;Ferlim;Fero-Folic 500;Ferogradumet;Ferralyn;Ferro-Gradumet;Ferro-Theron;Ferromyn;Ferrosand;Ferrous sulfate (1:1);Ferrous sulphate;Fersolate;Green Salts;Green vitriol;Iron monosulfate;Iron sulfate (1:1);Iron sulfate (FeSO4);Iron vitriol;Iron(2+) sulfate;Iron(2+) sulfate (1:1);Iron(II) sulfate;Irospan;Kesuka;Microfer Spansule;Odophos;Plastufer;Quickfloc;Quickfloc (salt);SFE 171;Slow-Fe;Sulferrous;Sulfuricacid iron salt (1:1);ferrous sulfate monohydrate;Ferrous sulfate heptahydrate;heptahydrate Ferrous sulfate;

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Identification
NameFerrous sulfate
CAS7720-78-7
SynonymsCombiron;Copperas;Duretter;Duroferon;Exsiccated ferrous sulfate;Exsiccated ferroussulphate;Feofol Spansule;Feosol;Feospan;Fer-In-Sol;Ferlim;Fero-Folic 500;Ferogradumet;Ferralyn;Ferro-Gradumet;Ferro-Theron;Ferromyn;Ferrosand;Ferrous sulfate (1:1);Ferrous sulphate;Fersolate;Green Salts;Green vitriol;Iron monosulfate;Iron sulfate (1:1);Iron sulfate (FeSO4);Iron vitriol;Iron(2+) sulfate;Iron(2+) sulfate (1:1);Iron(II) sulfate;Irospan;Kesuka;Microfer Spansule;Odophos;Plastufer;Quickfloc;Quickfloc (salt);SFE 171;Slow-Fe;Sulferrous;Sulfuricacid iron salt (1:1);ferrous sulfate monohydrate;Ferrous sulfate heptahydrate;heptahydrate Ferrous sulfate;
EINECS(EC#)231-753-5
Molecular FormulaFeSO4
Molecular Weight151.91
Safety Data

Risk R25
Safety

A human poison by ingestion. Moderately toxic to humans by an unspecified route. An experimental poison by ingestion, intraduodenal, intraperitoneal, intravenous, and subcutaneous routes. Human systemic effects by ingestion: aggression, somnolence, brain recording changes, diarrhea, nausea or vomiting, bleeding from the stomach, coma. Questionable carcinogen with experimental tumorigenic data. Experimental teratogenic and reproductive effects. Mutation data reported. Potentially explosive reaction with methyl isocyanoacetate at 25°. May ignite on contact with arsenic trioxide + sodium nitrate. When heated to decomposition it emits toxic fumes of SOx.
Risk Statements: 25?
R25 :Toxic if swallowed.
Safety Statements: 45?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child LDLo oral 390mg/kg (390mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANOREXIA (HUMAN		 Journal of Pediatrics. Vol. 64, Pg. 218, 1964.
?
child LDLo oral 435mg/kg (435mg/kg) BEHAVIORAL: COMA

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"		 Journal of Pediatrics. Vol. 95, Pg. 138, 1979.
?
child LDLo oral 699mg/kg (699mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

CARDIAC: OTHER CHANGES

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION		 Journal of Forensic Sciences. Vol. 27, Pg. 955, 1982.
?
child TDLo oral 20mg/kg (20mg/kg) BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA		 Journal of Pediatrics. Vol. 94, Pg. 147, 1979.
?
child TDLo oral 150mg/kg (150mg/kg) BEHAVIORAL: COMA

GASTROINTESTINAL: NAUSEA OR VOMITING

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"		 New England Journal of Medicine. Vol. 273, Pg. 1124, 1965.
?
child TDLo oral 250mg/kg (250mg/kg) GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

GASTROINTESTINAL: PERITONITIS		 Clinical Toxicology. Vol. 8, Pg. 3, 1975.
?
child TDLo oral 736mg/kg (736mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

VASCULAR: SHOCK		 Indian Journal of Pediatrics. Vol. 64, Pg. 485, 1997.
?
child TDLo oral 750mg/kg (750mg/kg) CARDIAC: PULSE RATE

GASTROINTESTINAL: NAUSEA OR VOMITING

VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION		 Journal of Toxicology, Clinical Toxicology. Vol. 33, Pg. 61, 1995.
?
child TDLo oral 68640mg/kg/5Y (68640mg/kg) LIVER: OTHER CHANGES Pediatrics. Vol. 105, Pg. 429, 2000.
?
dog LD50 intravenous 79mg/kg (79mg/kg) ? American Journal of the Medical Sciences. Vol. 241, Pg. 296, 1961.
?
guinea pig LD50 oral 1200mg/kg (1200mg/kg) ? Clinical Pediatrics Vol. 5, Pg. 485, 1966.
?
infant LDLo oral 4400ug/kg (4.4mg/kg) BEHAVIORAL: COMA

GASTROINTESTINAL: NAUSEA OR VOMITING

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"		 American Journal of Emergency Medicine. Vol. 6, Pg. 513, 1988.
man LDLo unreported 441mg/kg (441mg/kg) ? "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
mouse LD50 intraperitoneal 106mg/kg (106mg/kg) ? Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.
?
mouse LD50 intravenous 112mg/kg (112mg/kg) ? American Journal of the Medical Sciences. Vol. 241, Pg. 296, 1961.
?
mouse LD50 oral 680mg/kg (680mg/kg) ? British Journal of Pharmacology and Chemotherapy. Vol. 24, Pg. 352, 1965.
?
mouse LD50 subcutaneous 60300ug/kg (60.3mg/kg) ? Drugs in Japan Vol. 6, Pg. 888, 1982.
rabbit LDLo intraduodenal 200mg/kg (200mg/kg) CARDIAC: CARDIAC OUTPUT

VASCULAR: REGIONAL OR GENERAL ARTERIOLAR CONSTRICTION		 Toxicology and Applied Pharmacology. Vol. 66, Pg. 329, 1982.
?
rat LD50 oral 319mg/kg (319mg/kg) ? Journal of Pediatrics. Vol. 69, Pg. 663, 1966.
?
rat LD50 subcutaneous 155mg/kg (155mg/kg) ? Drugs in Japan Vol. 6, Pg. 888, 1982.
women LDLo oral 60mg/kg (60mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

GASTROINTESTINAL: NAUSEA OR VOMITING		 Human Toxicology. Vol. 7, Pg. 281, 1988.
?
women LDLo oral 540mg/kg (540mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: PERITONITIS		 Journal of Pediatric Surgery. Vol. 13, Pg. 720, 1978.
?
women TDLo oral 10560ug/kg (10.56mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH JAMA, Journal of the American Medical Association. Vol. 236, Pg. 2320, 1976.
?
women TDLo oral 600mg/kg (600mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: AGGRESSION		 JAMA, Journal of the American Medical Association. Vol. 229, Pg. 1333, 1974.
?
women TDLo oral 960mg/kg/9W-I (960mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"

LIVER: OTHER CHANGES		 New England Journal of Medicine. Vol. 339, Pg. 269, 1998.

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