Metoprine cas no:7761-45-7

Synonyms: Metoprine;methodichlorophen;2,4-DIAMINO-5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE;BW-50-197;DDMP;NSC-19494;U-197

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Identification
Chemical Properties
Safety Data
Toxicity

Identification

NameMetoprine
CAS7761-45-7
SynonymsMetoprine;methodichlorophen;2,4-DIAMINO-5-(3,4-DICHLOROPHENYL)-6-METHYLPYRIMIDINE;BW-50-197;DDMP;NSC-19494;U-197
Molecular FormulaC11H10Cl2N4
Molecular Weight0

Chemical Properties

refractive index1.678

Safety Data

Safety

Poison by subcutaneous and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl⁻ and NO_x.

Toxicity

1.	cyt-hmn-unr 2800 µg/kg	RBBIAL Revista Brasileira de Biologia. 25 (1965),145.
2.	orl-rat TDLo:2500 µg/kg (7D preg):TER	PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 87 (1954),571.
3.	orl-rat TDLo:5 mg/kg (8-9D preg):REP	PSEBAA Proceedings of the Society for Experimental Biology and Medicine. 87 (1954),571.
4.	ipr-rat LD50:7 mg/kg	14XBAV International Congress of Chemotherapy Stuttgart.: Thieme,1964,367.
5.	scu-mus LD50:50 mg/kg	CTRRDO Cancer Treatment Reports. 60 (1976),547.

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