| cat |
LDLo |
unreported |
4mg/kg (4mg/kg) |
|
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 102, Pg. 262, 1929. |
| dog |
LD50 |
intravenous |
202mg/kg (202mg/kg) |
|
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. |
| dog |
LDLo |
parenteral |
128mg/kg (128mg/kg) |
CARDIAC: OTHER CHANGES
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
GASTROINTESTINAL: OTHER CHANGES |
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 102, Pg. 262, 1929. |
| dog |
LDLo |
unreported |
600ug/kg (0.6mg/kg) |
|
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 102, Pg. 262, 1929. |
| guinea pig |
LD50 |
oral |
916mg/kg (916mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 36(9), Pg. 15, 1971. |
| guinea pig |
LDLo |
subcutaneous |
180mg/kg (180mg/kg) |
|
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. |
| guinea pig |
LDLo |
unreported |
60mg/kg (60mg/kg) |
|
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 102, Pg. 262, 1929. |
| mouse |
LD50 |
intramuscular |
255mg/kg (255mg/kg) |
|
Russian Pharmacology and Toxicology Vol. 38, Pg. 221, 1975. |
| mouse |
LD50 |
intraperitoneal |
121mg/kg (121mg/kg) |
|
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 244, Pg. 17, 1962. |
| mouse |
LD50 |
intravenous |
38mg/kg (38mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
BEHAVIORAL: ATAXIA |
Acta Radiologica. Vol. 38, Pg. 770, 1997. |
| mouse |
LD50 |
oral |
1031mg/kg (1031mg/kg) |
BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 36(9), Pg. 15, 1971. |
| mouse |
LDLo |
subcutaneous |
210mg/kg (210mg/kg) |
|
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. |
| rabbit |
LDLo |
intravenous |
64800ug/kg (64.8mg/kg) |
|
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. |
| rabbit |
LDLo |
parenteral |
41mg/kg (41mg/kg) |
CARDIAC: OTHER CHANGES
GASTROINTESTINAL: OTHER CHANGES
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION |
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 102, Pg. 262, 1929. |
| rabbit |
LDLo |
subcutaneous |
180mg/kg (180mg/kg) |
|
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975. |
| rabbit |
LDLo |
unreported |
6500ug/kg (6.5mg/kg) |
|
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 102, Pg. 262, 1929. |
| rat |
LD50 |
intramuscular |
700mg/kg (700mg/kg) |
|
Russian Pharmacology and Toxicology Vol. 38, Pg. 221, 1975. |
| rat |
LD50 |
intraperitoneal |
147mg/kg (147mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991. |
| rat |
LD50 |
intravenous |
92600ug/kg (92.6mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991. |
| rat |
LD50 |
oral |
250mg/kg (250mg/kg) |
|
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 26(12), Pg. 8, 1961. |
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