dog
|
LDLo
|
intravenous
|
60mg/kg (60mg/kg)
|
|
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
|
frog
|
LD50
|
subcutaneous
|
211mg/kg (211mg/kg)
|
|
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
|
guinea pig
|
LD50
|
intraperitoneal
|
104mg/kg (104mg/kg)
|
behavioral: somnolence (general depressed activity)
behavioral: anorexia (human)
behavioral: muscle weakness
|
AMA Archives of Industrial Health. Vol. 15, Pg. 9, 1957.
|
mouse
|
LD50
|
intraperitoneal
|
97849ug/kg (97.849mg/kg)
|
|
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.
|
mouse
|
LD50
|
oral
|
5277mg/kg (5277mg/kg)
|
|
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
|
mouse
|
LDLo
|
subcutaneous
|
4gm/kg (4000mg/kg)
|
|
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 188, Pg. 465, 1938.
|
rat
|
LD50
|
intravenous
|
6262ug/kg (6.262mg/kg)
|
liver:"hepatitis (hepatocellular necrosis), diffuse"
|
Acta Physiologica Polonica. Vol. 32, Pg. 205, 1981.
|
rat
|
LD50
|
oral
|
2111mg/kg (2111mg/kg)
|
|
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
|
rat
|
LDLo
|
subcutaneous
|
4gm/kg (4000mg/kg)
|
behavioral: tremor
behavioral:excitement
lungs,thorax,orrespiration: other changes
|
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 100, Pg. 230, 1923.
|