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2,2'-Azobis(2-methylpropionitrile) cas no:78-67-1

Synonyms: 2,2-Azobisisobutyronitrile; AIBN; Azo-iso-butyronitrile; 2,2-dimethyl-2,2-azodipropiononitrile; 2,2-Azobsisobutyronitril; 2,2-Azodi(isobutyronitrile); 2,2'-Azodiisobutyronitrile; Azo two different nitrile

Identification
Name2,2'-Azobis(2-methylpropionitrile)
CAS78-67-1
Synonyms2,2-Azobisisobutyronitrile; AIBN; Azo-iso-butyronitrile; 2,2-dimethyl-2,2-azodipropiononitrile; 2,2-Azobsisobutyronitril; 2,2-Azodi(isobutyronitrile); 2,2'-Azodiisobutyronitrile; Azo two different nitrile
EINECS(EC#)201-132-3
Molecular FormulaC8H12N4
Molecular Weight164.21
Chemical Properties
Appearancewhite solid
refractive index1.49
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass4.1
Safety Data

Hazard E:Explosive
Risk R2;R11;R20/22;R52/53
Safety

Poison by intraperitoneal route. Moderately toxic by ingestion. Easily oxidized, unstable. Violent exothermic decomposition when heated. Solution in acetone may decompose explosively. Explodes when heated with heptane. When heated to decomposition it emits toxic fumes of NOx and CN?. See also NITRILES. A free-radical generator.
Hazard Codes:?ExplosiveE,HarmfulXn
Risk Statements: 2-11-20/22-52/53?
R2:Risk of explosion by shock, friction, fire or other source of ignition.?
R11:Highly flammable.?
R20/22:Harmful by inhalation and if swallowed.?
R52/53:Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 39-41-47-61?
S39:Wear eye / face protection.?
S41:In case of fire and / or explosion do not breathe fumes.?
S47:Keep at temperature not exceeding...?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3234 4.1
WGK Germany: 2
RTECS: UG0800000
F: 4.4
HazardClass: 4.1
PackingGroup: II


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo subcutaneous 50mg/kg (50mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Toxikologie. Vol. 16, Pg. 367, 1957.
mouse LD50 intraperitoneal 25mg/kg (25mg/kg) ? National Technical Information Service. Vol. AD691-490,
mouse LD50 oral 700mg/kg (700mg/kg) ? "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 146, 1989.
mouse LDLo subcutaneous 40mg/kg (40mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Toxikologie. Vol. 16, Pg. 367, 1957.
rabbit LDLo subcutaneous 50mg/kg (50mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Toxikologie. Vol. 16, Pg. 367, 1957.
rat LC inhalation > 12gm/m3/4H (12000mg/m3) SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE

BEHAVIORAL: EXCITEMENT
National Technical Information Service. Vol. OTS0555369,
rat LD50 intraperitoneal 25mg/kg (25mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
National Technical Information Service. Vol. OTS0555369,
rat LD50 oral 100mg/kg (100mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA
National Technical Information Service. Vol. OTS0555369,
rat LDLo subcutaneous 30mg/kg (30mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Toxikologie. Vol. 16, Pg. 367, 1957.

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