Aztreonam cas no:78110-38-0
Synonyms: 2-[[(2-amino-1,3-thiazol-4-yl)-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-azetidin-3-yl]carbamoyl]methylidene]amino]oxy-2-methyl-propanoic acid;Aztreonamum [Latin];Aztreonam [USAN:BAN:INN:JAN];Dynabiotic;Propanoic acid, 2-(((1-(2-amino-4-thiazolyl)-2-((2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)-2-methyl-, (2S-(2alpha,3beta(Z)))-;(Z)-2-((((2-Amino-4-thiazolyl)(((2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid;Aztreonam ;azthreonam;Primbactam;Monobactam;2-[[[(Z)-1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid;Azactam;[2S-[2alpha,3beta(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid;Aztreonam Pure;Azteronam;Aztreonam L-Arginine;
NameAztreonam
CAS78110-38-0
Synonyms2-[[(2-amino-1,3-thiazol-4-yl)-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-azetidin-3-yl]carbamoyl]methylidene]amino]oxy-2-methyl-propanoic acid;Aztreonamum [Latin];Aztreonam [USAN:BAN:INN:JAN];Dynabiotic;Propanoic acid, 2-(((1-(2-amino-4-thiazolyl)-2-((2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino)-2-oxoethylidene)amino)oxy)-2-methyl-, (2S-(2alpha,3beta(Z)))-;(Z)-2-((((2-Amino-4-thiazolyl)(((2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid;Aztreonam ;azthreonam;Primbactam;Monobactam;2-[[[(Z)-1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid;Azactam;[2S-[2alpha,3beta(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid;Aztreonam Pure;Azteronam;Aztreonam L-Arginine;
EINECS(EC#)278-839-9
Molecular FormulaC13H17N5O8S2
Molecular Weight435.43
Appearancewhite to off-white crystals
storage tempStore at 0-5°C
Hazard Xn
Risk R20/21/22
Safety
Moderately toxic by several routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.
Hazard Codes??
Xn
Risk Statements? 20/21/22-36/37/38
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements? 22-24/25-36-26
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.?
S36:Wear suitable protective clothing.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
WGK Germany: 2
RTECS: UA2451400
HS Code 29419000
| 1. |
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ivn-rat TDLo:1100?mg/kg (7-17?D preg):TER
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NKRZAZ ?? Chemotherapy (Tokyo). 33 (Suppl 1)(1985),203. |
| 2. |
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ipr-rat LD50:2549?mg/kg
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NKRZAZ ?? Chemotherapy (Tokyo). 33 (Suppl 1)(1985),143. |
| 3. |
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scu-rat LD50:3154?mg/kg
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NKRZAZ ?? Chemotherapy (Tokyo). 33 (Suppl 1)(1985),143. |
| 4. |
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ivn-rat LD50:2001?mg/kg
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KSRNAM ?? Kiso to Rinsho. Clinical Report. 19 (1985),468. |
| 5. |
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ipr-mus LD50:2897?mg/kg
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??? |
NKRZAZ ?? Chemotherapy (Tokyo). 33 (Suppl 1)(1985),143. |
| 6. |
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scu-mus LD50:3906?mg/kg
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??? |
NKRZAZ ?? Chemotherapy (Tokyo). 33 (Suppl 1)(1985),143. |
| 7. |
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ivn-mus LD50:1963?mg/kg
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NKRZAZ ?? Chemotherapy (Tokyo). 33 (Suppl 1)(1985),143. |
